Multifunctional incretin peptides in therapies for type 2 diabetes, obesity and associated co-morbidities - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40081498/
Recent studies with peptide-based incretin therapies have focussed mainly on the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide and the dual agonist tirzepatide that engages receptors for GLP-1 and glucose-dependent insulinotropic...
This review highlights recent advances in incretin-based therapies, showcasing GLP-1, GIP, and multi-receptor agonists that improve glycemic control, weight loss, and comorbid conditions, offering promising future treatments for diabetes and obesity.
Effects of different treatment measures on the efficacy of diabetic foot ulcers: a network meta-analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39377075/
Due to the particularity of the wound of DFU, the standard of care is not effective, but the new treatment scheme has a remarkable effect in many aspects. And the...
This meta-analysis ranked treatments for diabetic foot ulcers, showing that combinations like PRP+NPWT and UD+NPWT outperform standard care in healing, reducing complications, and shortening recovery, without increasing adverse reactions.
Continuous and Flash Glucose Monitoring in Adults at Risk of Type 2 Diabetes: A Scoping Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39960213/
Existing published studies deploying glucose monitoring technologies show promise in supporting interventions aimed at preventing T2DM in at-risk adults. Further robust studies are required to confirm the long-term acceptability and...
CGM and FGM show promise in preventing type 2 diabetes in at-risk adults by improving glucose control and behaviors, but more high-quality studies are needed to confirm long-term effectiveness and feasibility.
Continuous Glucose Monitoring Metrics for Pregnancies Complicated by Diabetes: Critical Appraisal of Current Evidence - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38606830/
Ascertaining the utility of continuous glucose monitoring (CGM) in pregnancy complicated by diabetes is a rapidly evolving area, as the prevalence of type 1 diabetes (T1D), type 2 diabetes (T2D),...
Continuous glucose monitoring improves outcomes in type 1 diabetes pregnancies, but its value in type 2 and gestational diabetes remains unclear, with research needed on targets, metrics, and clinical impact.
Insulin Resistance in Type 1 Diabetes: Pathophysiological, Clinical, and Therapeutic Relevance - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39998445/
People with type 1 diabetes (T1D) are usually considered to exclusively exhibit β-cell failure, but they frequently also feature insulin resistance. This review discusses the mechanisms, clinical features, and therapeutic...
Insulin resistance in type 1 diabetes involves metabolic and autoimmune factors, contributes to complications, and may benefit from targeted treatments like insulin pumps or adjunct therapies, despite current limitations in clinical use.