Type 2 Diabetes Mellitus: New Pathogenetic Mechanisms, Treatment and the Most Important Complications - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39940862/
Type 2 diabetes mellitus (T2DM), a prevalent chronic disease affecting over 400 million people globally, is driven by genetic and environmental factors. The pathogenesis involves insulin resistance and β-cell dysfunction,...
Type 2 diabetes mellitus (T2DM) involves insulin resistance and β-cell dysfunction. Management includes lifestyle changes, cognitive-behavioral therapy, and advanced therapies to control glycemia, weight, and cardiovascular risk while preventing complications.
Physical activity guidelines for adults with type 2 Diabetes: Systematic review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39746550/
While guidelines consistently recommended aerobic exercise, there was limited emphasis on strength and flexibility exercises. Significant limitations in methodological and reporting quality were noted, especially in stakeholder involvement and applicability....
This systematic review analyzed 15 guidelines on physical activity for T2D, highlighting aerobic exercise recommendations. Methodological limitations were noted, emphasizing the need for standardized FITT frameworks and improved guideline development.
Non-pharmacological management strategies for type 2 diabetes in children and young adults: A systematic review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39961515/
Evidence for non-pharmacological management of youth onset type 2 diabetes is scarce. Available evidence demonstrated that VLED is associated with improved glycemia and weight loss. The role of social support...
This systematic review found limited evidence for non-pharmacological management of youth-onset type 2 diabetes, with very low-energy diets improving HbA1c and weight, while other interventions showed mixed effects on glycemia and well-being.
Key biomarkers in type 2 diabetes patients: A systematic review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39355932/
Type 2 diabetes mellitus (T2DM) is not just a local health issue but a significant global health burden, affecting patient outcomes and clinical management worldwide. Despite the wealth of studies...
This review analyzes T2DM biomarkers in haematological, protein, cytokine, and lipid profiles, highlighting inflammation, altered cell counts, and dyslipidemia, providing insights for innovative diagnostic and prognostic diabetes management strategies.
Tirzepatide for overweight and obesity management - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39632534/
Tirzepatide marks a new era in overweight/obesity treatment, enabling many to achieve ≥ 20% weight loss. It is well-tolerated with a safety profile similar to GLP-1 receptor agonists. Tirzepatide also...
Tirzepatide, a dual GLP-1/GIP agonist, enables ≥20% weight loss with improved obesity-related complications. The SURMOUNT program highlights its efficacy, safety, and potential in obesity and type 2 diabetes management.