Current barriers to initiating insulin therapy in individuals with type 2 diabetes - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38559691/
Insulin is an essential drug in the treatment of diabetes, often necessary for managing hyperglycemia in type 2 diabetes mellitus (T2DM). It should be considered in cases of severe hyperglycemia...
Insulin is essential in T2DM management, but barriers delay initiation. Once-weekly insulins like icodec and BIF may improve adherence, reduce therapeutic inertia, and enhance glycemic control by minimizing hypoglycemia risk and injection burden.
Early effective intervention can significantly reduce all-cause mortality in prediabetic patients: a systematic review and meta-analysis based on high-quality clinical studies - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38495794/
https://www.crd.york.ac.uk/prospero, identifier CRD42020160985.
This systematic review and meta-analysis evaluates early lifestyle or drug interventions for prediabetes, showing significant reductions in all-cause mortality, cardiovascular events, and microvascular complications, particularly for women and younger individuals.
Impact of Combined Prebiotic Galacto-Oligosaccharides and Bifidobacterium breve-Derived Postbiotic on Gut Microbiota and HbA1c in Prediabetic Adults: A Double-Blind, Randomized, Placebo-Controlled Study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39064648/
The complex interactions between intestinal microbiota and metabolic disorders are well-documented, with implications for glucose metabolism, energy expenditure, and intestinal permeability. Prebiotics induce beneficial changes in gut microbiota composition in...
A 12-week dietary fiber supplement with konjac glucomannan, galacto-oligosaccharides, and Bifidobacterium breve improved gut microbiota diversity, reduced HbA1c and FPG levels, suggesting potential in managing prediabetes.
cgm are certainly one of the causes of improvement in our T2DM patients mostly on basal or MDI insulin schr=edules but they have also shown benefit in those who require dietary adjustments, therefore the need of OTC CGM's lately additions to the market. Certainly the SGLT2i are what the statins were in the 80's, becoming a universal addition to...
The Role of Type 2 Diabetes Mellitus-Related Risk Factors and Drugs in Hepatocellular Carcinoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38268569/
With changes in modern lifestyles, type 2 diabetes mellitus (T2DM) has become a global epidemic metabolic disease, and hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths...
This review explores T2DM-related risk factors, anti-DM drugs, and their mechanisms in hepatocellular carcinoma (HCC), highlighting molecular pathways, potential biomarkers, and novel therapeutic strategies to improve patient prognosis.