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Trans-Ancestral Genetic Risk Factors for Treatment-Related Type 2 Diabetes Mellitus in Survivors of Childhood Cancer

Trans-Ancestral Genetic Risk Factors for Treatment-Related Type 2 Diabetes Mellitus in Survivors of Childhood Cancer

Source : https://pubmed.ncbi.nlm.nih.gov/38652878/

Our findings suggest therapy-related genetic risks contribute to the increased T2D burden among non-Hispanic Black childhood cancer survivors. Additional study of how therapy-related genetic susceptibility contributes to this disparity is...

Therapy-related genetic risks contribute to the increased burden of type 2 diabetes among non-Hispanic Black pediatric survivors of cancer.

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GL glargine was similar in terms of immunogenicity, efficacy, and safety, based on the current study.

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Prediction of New-Onset Heart Failure in Patients With Type 2 Diabetes Derived From ALTITUDE and CANVAS

Prediction of New-Onset Heart Failure in Patients With Type 2 Diabetes Derived From ALTITUDE and CANVAS

Source : https://pubmed.ncbi.nlm.nih.gov/38584567/

In patients with T2D, higher NT-proBNP level, TnT level and BMI are independent and externally validated predictors of new-onset HF, including patients using an SGLT2 inhibitor. This newly developed model...

In patients with type 2 diabetes, higher NT-proBNP level, troponin T level, and BMI are independent and externally validated predictors of new-onset HF, including patients taking sodium-glucose cotransporter 2 inhibitors.

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Semaglutide in Patients With Obesity-Related Heart Failure and Type 2 Diabetes

Semaglutide in Patients With Obesity-Related Heart Failure and Type 2 Diabetes

Source : https://pubmed.ncbi.nlm.nih.gov/38587233/

Among patients with obesity-related heart failure with preserved ejection fraction and type 2 diabetes, semaglutide led to larger reductions in heart failure-related symptoms and physical limitations and greater weight loss...

Among patients with obesity-related HF with preserved ejection fraction and type 2 diabetes, semaglutide led to larger reductions in HF-related symptoms and physical limitations and greater weight loss than placebo at 1 year.

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Experts warn that patients with obesity and type 2 diabetes do not have the luxury of waiting until 2041 for comprehensive coverage of metabolic surgery.