The Effectiveness of GLP-1 Receptor Agonist Semaglutide on Body Composition in Elderly Obese Diabetic Patients: A Pilot Study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36135828/
doi: 10.3390/medicines9090047. 1 Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University, Yufu City 879-5593, Oita, Japan. 2 Faculty of Medicine, Oita University, Yufu City 879-5593, Oita,...
Conclusions: These results suggest that the GLP1-RA semaglutide effectively reduces body adiposity while maintaining the MM in obese type 2 diabetic patients.
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Dr Hamid3yrInteresting article that shows semaglutide effectively reduces body adiposity
Care Endpoints in Adults With Type 2 Diabetes: Screening and Therapeutic Targets at a Canadian Tertiary Diabetes Care Centre
Source : https://www.canadianjournalofdiabetes.com/article/S1499-2671(22)00211-8/fulltext
Although national diabetes guidelines recommend targets for various health parameters, studies have demonstrated a gap between recommendations and real-life practice. The objectives of the present study were to: 1) assess...
Conclusions: Patients with T2DM at the MUHC receive guideline-based measurements of health parameters more frequently than at other institutions. Achievement of target values was closer to that seen by Canadian specialists than by primary care. Although further analyses are necessary to help implement effective strategies for improvement,...
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Dr Hamid3yrInteresting article, but further analyses are necessary to help implement effective strategies for improvement
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Amy Gonzales, Physician3yrScreening and counseling are important in preventing diabetes.
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Aldehyde Dehydrogenase 2 Activator Augments the Beneficial Effects of Empagliflozin in Mice with Diabetes-Associated HFpEF - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36142350/
1 Division of Hypertension and Vascular Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI 48202, USA. 2 Department of Physiology, Wayne State University, Detroit, MI 48202, USA....
Conclusions: AMP-activated protein kinase (AMPK) pathways in ALDH2*2 mice with diabetes-associated HFpEF. This combination was even more effective than EMP alone. Our data indicate that ALDH2 activation along with the treatment of hypoglycemic agents may be a salient strategy to alleviate diabetes-associated HFpEF.
Real-world effectiveness of IDegLira compared with intensified conventional insulin therapy in adults with type 2 diabetes: a retrospective cohort study - BMC Endocrine Disorders
Source : https://bmcendocrdisord.biomedcentral.com/articles/10.1186/s12902-022-01139-8
Background IDegLira is a fixed-ratio combination of insulin degludec and liraglutide with proven efficacy against simpler regimens and non-inferiority against basal-bolus insulin therapy. However, the evaluation of its real-world effectiveness...
Conclusions: Treatment with IDegLira over 18 months resulted in greater HbA1c reductions, weight loss versus gain, and a lower rate of hypoglycaemia versus ICT in people with type 2 diabetes.
Influence of sodium-glucose Co-transporter 2 inhibitors on clinical and biochemical markers of dehydration during the Holy Ramadan
Source : https://www.sciencedirect.com/science/article/abs/pii/S187140212200220X?via=ihub
Excess glucose excretion and diuresis with sodium-glucose co-transporter 2 inhibitors may cause dehydration during Ramadan. * Clinical and biochemical markers of dehydration existed with sodium-glucose co-transporter 2 inhibitors during Ramadan....
Conclusions: Significant clinical and biochemical markers of dehydration were noticed among users of SGLT2i during the Holy Ramadan.
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Dr Hamid3yrImportant study to detect the potential alteration of hydration status in adult Muslims with type 2 diabetes mellitus (T2D) who used SGLT2i during Ramadan.