Association of MRI‐based adrenal gland volume and impaired glucose metabolism in a population‐based cohort study
Source : https://onlinelibrary.wiley.com/doi/10.1002/dmrr.3528
Esther Askani , Susanne Rospleszcz , Wolfgang Rathmann , Annette Peters , Corinna Storz , Corresponding Author Corinna Storz Department of Neuroradiology, Medical Center - University of Freiburg, Faculty of...
Conclusions: Among the 4 GLP-1RAs, Semaglutide was the most cost-effective obesity medication.
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Dr Hamid3yrAdrenal gland volume may represent an indirect marker of impaired glucose metabolism and HPA axis dysfunction.
Association between SGLT2 Inhibitors vs DPP4 Inhibitors and Renal Outcomes Among Patients with Type 2 Diabetes - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35303075/
doi: 10.1210/clinem/dgac164. Online ahead of print. 1 Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. 2 Department of...
Conclusion: Compared to DPP4is, SGLT2is use was associated with reduced risks of ESRD and ARF, and a slower eGFR decline in a real-world setting. The associations remained significant in patients with or without pre-index rapid eGFR decline.
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Dr Hamid3yrDiabetic kidney disease is a major burden among diabetic patients. Sodium-glucose co-transporter 2 inhibitors (SGLT2is) were shown to reduce renal outcomes in clinical trials and real-world studies
Cost-effectiveness analysis of 4 GLP-1RAs in the treatment of obesity in a US setting
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8904982/
Ying Hu,# 1 , # ^ Shui-Lian Zheng,# 1 , # Xiao-Lan Ye, 1 Jia-Na Shi, 1 Xiao-Wei Zheng, 1 Han-Sheng Pan, 1 Yi-Wen Zhang, 1 , 2 Xiu-Li Yang,...
Efficacy of Off-Label Therapy for Non-alcoholic Fatty Liver Disease in Improving Non-invasive and Invasive Biomarkers: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35280867/
doi: 10.3389/fmed.2022.793203. 1 Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China. 2 Key Laboratory of Chinese Internal Medicine of Ministry of Education...
Conclusion: The network meta-analysis provided evidence for the efficacy of vitamin E, pioglitazone, SGLT2 inhibitors, and GLP-1 receptor agonists in treating patients with NAFLD. To find the best guide-level drugs, it is necessary to include more RCTs with these off-label drugs, so that patients and clinicians can make optimal decisions...
Secular trends in global burden of diabetes attributable to particulate matter pollution from 1990 to 2019 - Environmental Science and Pollution Research
Source : https://link.springer.com/article/10.1007/s11356-022-19510-6
Increasing evidence suggests an association between fine particulate matter (PM2.5) exposure and type 2 diabetes mellitus. However, there is still a lack of comparative evaluation regarding diabetes burden due to...
Conclusion/Relevance: The elderly and people in low-SDI countries suffered from the greatest burden of diabetes due to PM2.5 pollution. More targeted interventions should be taken by governments to reduce PM2.5 exposure and related diabetes burden.