Type 2 Diabetes Connect
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Type 2 Diabetes

Over 34 million1 Americans have diabetes, and 90-95%2 of them have Type 2 Diabetes. When diet and lifestyle changes fail to improve glycemic control, metformin3 is typically the first treatment prescribed. Several novel drugs and classes have emerged to treat Type 2 Diabetes after or in addition to metformin. These include GLP-1 receptor agonists, DPP-4 and SGLT2 inhibitors.

  • What factors do you consider when adding to or switching from metformin?
  • What have been your experiences with some of the newer/novel Type 2 Diabetes drugs and classes?

 

References:

  1. National Diabetes Statistics Report, 2020
  2. CDC Diabetes Basics, accessed 11 Jan 2022
  3. Mayo Clinic Type 2 Diabetes Diagnosis and Treatment, accessed 11 Jan 2022
  • 4yr
    Incretin therapy is key as there is a relative deficiency or decreased responsiveness in metabolic syndrome and type 2 DM. With the GIP moiety being added to the GLP-1 Show More
  • 4yr
    Rybelsus ( it is oral Ozempic Semaglutide ) has come up as a block buster diabetic medicine in both managing diabetes and Obeisty , having phenomenal results that Show More

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made a Post

4yr
Type 2 Diabetes

Over 34 million1 Americans have diabetes, and 90-95%2 of them have Type 2 Diabetes. When diet and lifestyle changes fail to improve glycemic control, metformin3 is typically the first treatment prescribed. Several novel drugs and classes have emerged to treat Type 2 Diabetes after or in addition to metformin. These include GLP-1 receptor agonists, DPP-4 and SGLT2 inhibitors.




  • What factors do you consider when adding to or switching from metformin?

  • What have been your experiences with some of the newer/novel Type 2 Diabetes drugs and classes?



 



References:




  1. National Diabetes Statistics Report, 2020

  2. CDC Diabetes Basics, accessed 11 Jan 2022

  3. Mayo Clinic Type 2 Diabetes Diagnosis and Treatment, accessed 11 Jan 2022


  • 4yr
    Incretin therapy is key as there is a relative deficiency or decreased responsiveness in metabolic syndrome and type 2 DM. With the GIP moiety being added to the GLP-1 Show More
  • 4yr
    Rybelsus ( it is oral Ozempic Semaglutide ) has come up as a block buster diabetic medicine in both managing diabetes and Obeisty , having phenomenal results that Show More

Show More Comments

  • Saved

made a Post

4yr
Type 2 Diabetes

Over 34 million1 Americans have diabetes, and 90-95%2 of them have Type 2 Diabetes. When diet and lifestyle changes fail to improve glycemic control, metformin3 is typically the first treatment prescribed. Several novel drugs and classes have emerged to treat Type 2 Diabetes after or in addition to metformin. These include GLP-1 receptor agonists, DPP-4 and SGLT2 inhibitors.




  • What factors do you consider when adding to or switching from metformin?

  • What have been your experiences with some of the newer/novel Type 2 Diabetes drugs and classes?



 



References:




  1. National Diabetes Statistics Report, 2020

  2. CDC Diabetes Basics, accessed 11 Jan 2022

  3. Mayo Clinic Type 2 Diabetes Diagnosis and Treatment, accessed 11 Jan 2022


  • 4yr
    Incretin therapy is key as there is a relative deficiency or decreased responsiveness in metabolic syndrome and type 2 DM. With the GIP moiety being added to the GLP-1 Show More
  • 4yr
    Rybelsus ( it is oral Ozempic Semaglutide ) has come up as a block buster diabetic medicine in both managing diabetes and Obeisty , having phenomenal results that Show More

Show More Comments

  • Saved

made a Post

4yr
Type 2 Diabetes

Over 34 million1 Americans have diabetes, and 90-95%2 of them have Type 2 Diabetes. When diet and lifestyle changes fail to improve glycemic control, metformin3 is typically the first treatment prescribed. Several novel drugs and classes have emerged to treat Type 2 Diabetes after or in addition to metformin. These include GLP-1 receptor agonists, DPP-4 and SGLT2 inhibitors.




  • What factors do you consider when adding to or switching from metformin?

  • What have been your experiences with some of the newer/novel Type 2 Diabetes drugs and classes?



 



References:




  1. National Diabetes Statistics Report, 2020

  2. CDC Diabetes Basics, accessed 11 Jan 2022

  3. Mayo Clinic Type 2 Diabetes Diagnosis and Treatment, accessed 11 Jan 2022


  • 4yr
    Incretin therapy is key as there is a relative deficiency or decreased responsiveness in metabolic syndrome and type 2 DM. With the GIP moiety being added to the GLP-1 Show More
  • 4yr
    Rybelsus ( it is oral Ozempic Semaglutide ) has come up as a block buster diabetic medicine in both managing diabetes and Obeisty , having phenomenal results that Show More

Show More Comments

  • Saved

4yr
Efficacy and safety of oral semaglutide by subgroups of patient characteristics in the PIONEER phase 3 programme - PubMed

Efficacy and safety of oral semaglutide by subgroups of patient characteristics in the PIONEER phase 3 programme - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35373893/

doi: 10.1111/dom.14710. Online ahead of print. 1 Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. 2 Novo Nordisk A/S, Søborg, Denmark. 3 Diabetes Centre, Institute for Clinical and...


Conclusions: Oral semaglutide demonstrated consistently greater HbA1c and body weight reductions across a range of patient characteristics, with greater HbA1c reductions seen at higher baseline HbA1c levels.