Source : https://pubmed.ncbi.nlm.nih.gov/39287729/
Diabetes has arisen as a noteworthy global health issue, marked by escalating incidence and mortality rates. Insulin, crucial for preserving euglycemia, acts as a vital energy provider for various tissues....
This review highlights iron’s adverse impact on insulin sensitivity and glucose metabolism, exploring molecular mechanisms, oxidative stress, and microelement influences, with evidence from population, animal, and clinical studies linking iron to diabetes.
decrease kidney function and proteinuria is risk factor for heart disease and kidney disease
In a phase 2b study, efruxifermin added to stable GLP-1RA therapy in MASH patients with T2D was safe and reduced hepatic fat fraction by 65% vs. 10% with GLP-1RA alone. It also improved noninvasive fibrosis and metabolic markers without impacting weight loss benefits.
Did you know? Statins are linked to a 9–12% increased risk of new-onset diabetes, particularly with long-term, high-dose use and in patients with impaired glucose regulation. Still, their cardiovascular benefits usually outweigh this risk, prompting continued use in most at-risk populations.
Could statins’ effects on insulin release and sensitivity explain their role in glucose abnormalities?
Could statins’ effects on insulin release and sensitivity explain their role in glucose abnormalities?
