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Prevalence and Trends of Type 2 Diabetes Mellitus and Prediabetes among Community-Dwelling Heart Failure Patients in the United States - PubMed

Prevalence and Trends of Type 2 Diabetes Mellitus and Prediabetes among Community-Dwelling Heart Failure Patients in the United States - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35041861/

doi: 10.1016/j.diabres.2022.109191. Online ahead of print. 1 Department of Nutritional Sciences, College of Family and Consumer Sciences, University of Georgia. 305 Sanford Drive, Dawson Hall, Athens, GA 30605, USA. Electronic...

#:~:text=Results: Prevalence rates of diagnosed,44.9%) of HF patients.

Our results suggest that the gut microbiota is imbalanced and its metabolite PAGln levels are increased in stroke patients with T2D, and T2D potentially aggravates stroke injury via an inflammatory response, which is associated with gut microbiota and its metabolite PAGln...

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    Prevention of and targeted intervention for T2DM among at-risk HF patients is needed, particularly among those of Hispanic origin
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    Key Points • Source: Diabetes Research and Clinical Practice • Conclusion/Relevance: “Prevalence rates of T2DM and prediabetes among community-dwelling HF patients in the U.S. remained high between 2005 and 2016. Prevention of and targeted Show More
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Preoperative plasma aldosterone predicts complete remission of type 2 diabetes after bariatric surgery - PubMed

Preoperative plasma aldosterone predicts complete remission of type 2 diabetes after bariatric surgery - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35016181/

Introduction: Bariatric surgery (BS) has beneficial effects on body weight and type 2 diabetes. However, 44-52%, 20-40%, and 19-25% of patients with type 2 diabetes who undergo sleeve gastrectomy, sleeve...



Discussion/Conclusion: Preoperative plasma aldosterone levels were related to the CR of type 2 diabetes after BS. Measuring plasma aldosterone levels preoperatively is useful for predicting the CR of type 2 diabetes after BS.

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Decline in renal function associated with cardiovascular autonomic neuropathy positively coordinated with proteinuria in patients with type 2 diabetes - PubMed

Decline in renal function associated with cardiovascular autonomic neuropathy positively coordinated with proteinuria in patients with type 2 diabetes - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34228899/

1 Department of Pharmacotherapy, Meiji Pharmaceutical University, Kiyose City, Japan. 2 Divisoin of Clinical Laboratory, The Institute for Medical Science, Asahi Life Foundation, Chuo-ku, Japan. 3 Department of Public Health...



Conclusion: "CAN strongly increased the risk of a 40% eGFR decline from baseline, especially in type 2 diabetes patients with macroproteinuria."


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Low fasting glucose-to-estimated average glucose ratio was associated with superior response to insulin degludec/aspart compared with basal insulin in patients with type 2 diabetes - PubMed

Low fasting glucose-to-estimated average glucose ratio was associated with superior response to insulin degludec/aspart compared with basal insulin in patients with type 2 diabetes - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34291584/

1 Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea. 2 Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Bundang...



Conclusions: "We observed that IDegAsp was more effective than basal insulin in patients with an FPG lower than predicted by HbA1c, which might be related with insulin deficiency and postprandial hyperglycemia in patients on basal insulin therapy."

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Glucolipotoxicity promotes the capacity of the glycerolipid/NEFA cycle supporting the secretory response of pancreatic beta cells - Diabetologia

Glucolipotoxicity promotes the capacity of the glycerolipid/NEFA cycle supporting the secretory response of pancreatic beta cells - Diabetologia

Source : https://link.springer.com/article/10.1007/s00125-021-05633-x

Aims/hypothesis Chronic exposure of pancreatic beta cells to high glucose and fatty acids has been proposed to induce glucolipotoxicity. However, contradictory results suggest adaptations of the beta cells, which might...



Conclusions/Interpretation: "Glucolipotoxic conditions promote the capacity of the glycerolipid/NEFA cycle thereby preserving part of the secretory response. The cycle of fat storage/mobilisation emerges as a mechanism helping the beta cell to cope with glucotoxic conditions.