Effect of glucagon-like peptide-1 receptor agonists on body weight in adults with obesity without diabetes mellitus-a systematic review and meta-analysis of randomized control trials - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35194917/
Clinical trials have investigated the weight loss effect of glucagon-like peptide-1 receptor agonists (GLP-1 RA) in adults with obesity without diabetes mellitus, but results for weight loss efficacy were varied....
Conclusion: The overall analysis results showed that GLP-1 RA improved glycemic control without increasing the risk of hypoglycemic events. Better control of blood pressure and plasma levels of LDL, HDL, and triglycerides was seen with GLP-1 RA treatment. Subgroup analysis showed greater treatment effect of semaglutide than liraglutide....
Usefulness of Empagliflozin Versus Oral Semaglutide for Prevention of Cardiovascular Mortality in Patients With Type 2 Diabetes Mellitus - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35197207/
Empagliflozin and oral semaglutide reduce the incidence of cardiovascular mortality (CVM) in patients with type 2 diabetes mellitus. However, these therapies impose a significant financial burden on healthcare systems. Therefore,...
Conclusion/Relevance: In conclusion, our findings suggest that empagliflozin provides better value for money than oral semaglutide to prevent CVM in patients with type 2 diabetes mellitus at the current United States prices of the interventions.
The efficacy and safety of once‐weekly semaglutide in Japanese subjects with type 2 diabetes by baseline age and body mass index
Source : https://onlinelibrary.wiley.com/doi/10.1111/jdi.13773
Daisuke Yabe , Yuichiro Yamada , Kohei Kaku , Tomoyuki Nishida , Toshihiro Sato , Yutaka Seino , Yutaka Seino Center for Diabetes, Endocrinology and Metabolism, Kansai Electric Power Hospital,...
Conclusions: In this post hoc analysis with modest subgroup numbers, OW semaglutide appeared consistently more efficacious versus comparators across age and BMI subgroups in Japanese patients, with a similar safety profile.
Semaglutide for weight loss and cardiometabolic risk reduction in overweight/obesity - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35175229/
doi: 10.1097/HCO.0000000000000955. Online ahead of print. 1 Department of Internal Medicine, Texas Tech University Health Sciences Center at El Paso, El Paso, Texas Division of Cardiovascular Medicine, North Shore-Long Island...
Summary: Semaglutide offers adults with obesity or overweight a new treatment in conjunction with a weight management program consisting of reduced calorie diet and increased physical activity.
Instructive lessons from the analysis of assistance in diabetes during the first phase of COVID-19 pandemic - Acta Diabetologica
Source : https://link.springer.com/article/10.1007/s00592-022-01855-6
Planning specific and periodical controls in diabetes is a common activity in most countries. Early diagnosis, treatment and follow-up of the disease is a principle of preventive medicine supported by...
Relevance: Planning specific and periodical controls in diabetes is a common activity in most countries. Early diagnosis, treatment and follow-up of the disease is a principle of preventive medicine supported by the totality of guidelines. Some previous studies have reported that not undergoing health check-ups was associated with worse...