9mo
Type 2 Diabetes Connect
8mo
The mechanism of C1q/TNF-related proteins (CTRPs) in atherosclerosis associated with type 2 diabetes mellitus - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41258160/
Increasing evidence suggests that C1q/tumor necrosis factor-related proteins (CTRPs), as the adipokine superfamily, are secreted by adipose tissues. They play an important role in diabetic cardiovascular pathology. Diabetic vascular complications...
CTRPs, adipokines altered in type 2 diabetes, influence atherosclerosis through effects on inflammation, metabolism, and vascular function; their heterogeneous expression highlights potential diagnostic and therapeutic roles in diabetic vasculopathy.
56yr
Fun Fact! Statin-associated liver injury (SILI) is rare, with true liver damage seen in just 1 in 1,000 to 1 in 10,000 patients. Though 2.8–3.1% show elevated liver enzymes, most cases are mild and resolve after stopping treatment. Interestingly, statins may offer protection against chronic liver diseases like cirrhosis.
Could statins play a dual role in both managing cholesterol and protecting liver health?
Could statins play a dual role in both managing cholesterol and protecting liver health?
9mo
Effect of metformin on free testosterone level in male diabetic patients: A comparative study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41204600/
When we consider the treatment of polycystic ovary syndrome (PCOS), one of our treatment options is metformin, which reduces free testosterone levels in PCOS patients. We were interested to know...
Metformin modestly increased free testosterone in male T2DM patients but significantly less than other antidiabetic drugs, suggesting it is inferior for improving testosterone levels and warrants further investigation.
9mo
Advances in lung health and sleep medicine: Key highlights from CHEST 2025
At CHEST 2025 in Chicago, pulmonology experts shared new insights in asthma, COPD, interstitial lung disease, pulmonary hypertension, and sleep medicine. Dr. Sandhya Khurana highlighted emerging asthma data—such as imaging-based reductions in mucus plugging and outcomes in severe asthma with nasal polyps—while also discussing the future of nanobody therapeutics. Dr. Cosmo Fowler reviewed GLP-1 RA–linked survival benefits in OSA.
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