Efficacy of clonidine in the treatment of children with tic disorder co-morbid with attention deficit hyperactivity disorder - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37203849/
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Conclusions: Clonidine effectively alleviates tic symptoms, reduces attention deficit and hyperactivity/impulsivity in children with tic disorder co-morbid attention deficit hyperactivity disorder, and features a high safety profile.
Analysis of Growth Velocity in Children with Attention-Deficit/Hyperactivity Disorder Treated for up to 12 Months with Serdexmethylphenidate/Dexmethylphenidate
Source : https://www.liebertpub.com/doi/10.1089/cap.2023.0012
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Conclusion: The overall effects of SDX/d-MPH on growth velocity (the change in weight and height from one time point to the next) were minimal, and the range of changes was not considered clinically significant.
Kappa Opioid Receptor Antagonism Rescues Genetic Perturbation of Dopamine Homeostasis: Molecular, Physiological and Behavioral Consequences - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37205452/
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Relevance: Aberrant dopamine (DA) signaling is implicated in schizophrenia, bipolar disorder (BPD), autism spectrum disorder (ASD), substance use disorder, and attention-deficit/hyperactivity disorder (ADHD). Treatment of these disorders remains inadequate. We established that the human DA transporter (DAT) coding variant (DAT Val559),...
At the risk of challenging one of the 'sacred cows' of Psychiatry how many psychiatrists are familiar with the concept of a Diagnostic Hierarchy? See: See also: https://psychiatryletter.com/adult-add/