Conclusions: Our results suggest that PLMS are not more frequent in children with ADHD compared to TD children. A finding of frequent PLMS in a child with ADHD should therefore be considered a separate disorder and prompt specific diagnostic and therapeutic strategies.
Conclusions: Our findings provide support for the effect of stimulants on pupil diameter in a dose-dependent manner. No clinically significant differences in visual functions were found 1.5 hours after consumption of D-MPH. Institutional review board clinical trial refference no. 0122-17-TLV.
Prescription stimulant use during long-term opioid therapy and risk for opioid use disorder
Source : https://www.sciencedirect.com/science/article/pii/S277272462200097X?via=ihub
Dual use of prescription stimulants and opioids is increasing. * Stimulant and long-term opioid use may increase risk for opioid use disorder. * We studied risk for opioid use disorder...
Conclusions: Dual stimulant use among patients with LTOT does not increase risk for OUD. Stimulants prescribed for ADHD and other conditions may not worsen opioid outcomes for some patients with LTOT.
Safety and Tolerability of Serdexmethylphenidate/Dexmethylphenidate Capsules in Children with Attention-Deficit/Hyperactivity Disorder: A 12-Month, Open-Label Safety Study
Source : https://www.liebertpub.com/doi/10.1089/cap.2022.0076
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Conclusions: In this 1-year study, SDX/d-MPH was found to be safe and well tolerated and comparable with other methylphenidate products, with no unexpected safety findings. SDX/d-MPH also showed sustained efficacy during the 1-year treatment period. ClinicalTrials.gov identifier: NCT03460652.
Methylphenidate-Induced Menorrhagia in Twin Girls - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36817810/
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Conclusion: Menorrhagia is a rare adverse effect of methylphenidate use and clinicians should be aware of this phenomenon.