Dolutegravir monotherapy and weight gain in naive patients with <100,000 copies/ml HIV RNA:an extended follow-up
Source : https://www.liebertpub.com/doi/10.1089/AID.2021.0234
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Conclusion/Relevance: We previously reported our experience in 20 HIV-infected patients, naïve to HAART and with a zenith HIV RNA
Effectiveness of the Med Safety mobile application in improving adverse drug reaction reporting by healthcare professionals in Uganda: a protocol for a pragmatic cluster-randomised controlled trial
Source : https://bmjopen.bmj.com/content/12/7/e061725
Introduction Combination antiretroviral therapy (cART) has massively reduced HIV mortality. However, long-term cART increases the risk of adverse drug reactions (ADRs), which can lead to higher morbidity, mortality and healthcare...
Relevance: The Med Safety mobile application has been developed through the European Union’s Innovative Medicines Initiative WEB-Recognising Adverse Drug Reactions project to promote digital pharmacovigilance. This mobile application has been approved for ADR-reporting by Uganda’s National Drug Authority. However, the barriers and...
Uptake and Acceptability of MyChoices: Results of a Pilot RCT of a Mobile App Designed to Increase HIV Testing and PrEP Uptake Among Young American MSM - AIDS and Behavior
Source : https://link.springer.com/article/10.1007/s10461-022-03724-3
Young men who have sex with men (YMSM) remain at disproportionate risk for HIV acquisition in the United States (US), yet use of evidence-based prevention strategies, including routine HIV testing...
Conclusion: While not powered to assess efficacy, those in the MyChoices arm had 22% higher prevalence of HIV testing over follow-up compared to those in the SOC arm (NS). There was no difference in PrEP uptake. A fully-powered efficacy trial is warranted; if efficacy is demonstrated, the MyChoices app could be easily scaled to reach YMSM...
Adapting a Motivational Interviewing Intervention to Improve HIV Prevention Among Young, Black, Sexual Minority Men in Alabama: Protocol for the Development of the Kings Digital Health Intervention
Source : https://www.researchprotocols.org/2022/7/e36655
Background: African American or Black young men who have sex with men (BYMSM) are at a disproportionate risk for contracting HIV and have high rates of undiagnosed, and therefore untreated,...
Conclusions: The findings will inform next steps, that is, testing the Kings intervention for feasibility, acceptability, and preliminary effectiveness in a pilot hybrid type 1 effective-implementation randomized controlled trial. The study results will provide insights about important considerations for HIV prevention among BYMSM in the...
Transitioning women to first-line preferred TLD regimen is lagging in Sub-Saharan Africa - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35788648/
doi: 10.1093/cid/ciac555. Online ahead of print. 1 U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, USA. 2 Henry M. Jackson Foundation for the Advancement of...
Conclusions: Despite TLD being the WHO's preferred regimen since 2019, transition of women to potentially lifesaving TLD has been slower than men at certain clinical sites even after accounting for local eligibility criteria.