Treatment-Experienced Patients on Third-Line Therapy: A Retrospective Cohort of Treatment Outcomes at the HIV Advanced Treatment Centre, University Teaching Hospital, Zambia
Source : https://www.liebertpub.com/doi/10.1089/AID.2021.0208
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Conclusions: Treatment-experienced patients receiving TLART in Zambia achieved high rates of suppression despite high levels of HIV resistance mutations, illustrating TLART treatment effectiveness in the DTG era.
Adherence, Effectiveness and Safety of Dolutegravir Based Antiretroviral Regimens among HIV Infected Children and Adolescents in Tanzania - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35776522/
Objectives: This study aimed at assessing adherence, effectiveness, and safety of DTG-based HAART regimens among HIV-infected children and adolescents in Tanzania. Methods: This was a single-center prospective cohort study, conducted...
Conclusion: The majority of patients attained undetectable viral load 6 months after using DTG based regimen. DTG-based regimens were generally safe with few ADEs reported.
Low-level viremia and virologic failure among people living with HIV who received maintenance therapy with co-formulated bictegravir, emtricitabine and tenofovir alafenamide versus dolutegravir-based regimens
Source : https://www.sciencedirect.com/science/article/pii/S0924857922001431?via=ihub
Available online 1 July 2022, 106631 * The incidence of low-level viremia was similar between bictegravir- or dolutegravir-based ART. * Among PLWH receiving second generation INSTI, low-level viremia was not...
Conclusions: Among virally suppressed PLWH, the incidences of developing LLV or VF were similar after switch to dolutegravir- or bictegravir-based ART. Preexisting RAMs to nucleoside reverse-transcriptase inhibitors or the LLV events were not associated with subsequent VF.
Factors associated with uptake of contraceptives among HIV positive women on dolutegravir based anti-retroviral treatment-a cross sectional survey in urban Uganda - BMC Women's Health
Source : https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-022-01842-7
Background In May 2018, following the preliminary results of a study in Botswana that reported congenital anomalies in babies born to HIV-positive women taking dolutegravir drug, the WHO issued a...
Conclusion: We observed a low-level uptake of contraceptives, with injectables as the most used method. Family planning counseling and partner discussion on family planning were associated with contraceptive uptake among the women who used dolutegravir-based regimens. There is a need for more strategies to integrate FP services and increase male...
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Dr Hamid3yrFamily planning counseling and partner discussion on family planning are important
Contrasting Comprehension of HIV Research by Adolescents, Young Adults, and Caregivers in Western Kenya: A Cross-sectional Analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35767728/
Adolescent participation in research is critical to inform interventions that improve outcomes for this group. Adolescents and young adults living with HIV often present to care without caregivers, yet caregiver...
Conclusion: Our findings suggest that for low-risk research, waiving caregiver permission requirements will not compromise the ethical need to ensure understanding of research before enrollment and may allow adolescents greater access to potential research benefits.
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Dr Hamid3yrAdolescents and young adults living with HIV often present to care without caregivers