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Statins provide protective immune benefits for females

Statins provide protective immune benefits for females

Source : https://www.eurekalert.org/news-releases/962681

When we have too much cholesterol, it can build up in the walls of our arteries and cause cardiovascular disease. But cholesterol molecules play a critical role in our cells'...


Conclusion: Andersen found that statins, commonly prescribed lipid-lowering drugs, provide a protective immune function in females.

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  • 3yr
    This study and it’s findings is especially significant because historically, drug trials have used predominantly male participants
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Relation Between Sex, Menopause, and White Matter Hyperintensities

Relation Between Sex, Menopause, and White Matter Hyperintensities

Source : https://n.neurology.org/content/99/9/e935.abstract

Background and Objectives Mounting evidence implies that there are sex differences in white matter hyperintensity (WMH) burden in older people. Questions remain regarding possible differences in WMH burden between men...


Discussion: After menopause, women displayed a higher burden of WMH than contemporary premenopausal women and men and an accelerated increase in WMH. Sex-specific effects of uncontrolled hypertension on WMH were not related to menopause.

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Immunization for midlife women - PubMed

Immunization for midlife women - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35998660/

Objective: Menopause occurs at a critical juncture in life when preventative health care can have a major impact. However, recommendations for immunizations are often neglected, leading to unnecessary morbidity and...


Conclusion: As women often seek medical attention at menopause because of changes in their physiology that require attention, it is the ideal time to discuss the importance of immunization.

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Differing effects of oral conjugated equine estrogen and transdermal estradiol on vitamin D metabolism in postmenopausal women: a 4-year longitudinal study - PubMed

Differing effects of oral conjugated equine estrogen and transdermal estradiol on vitamin D metabolism in postmenopausal women: a 4-year longitudinal study - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35969885/

Directly measured free 25-hydroxyvitamin D levels, but not serum total 25-hydroxyvitamin D levels, are different within the first 12 months of estrogen replacement depending on the preparation. However, this difference...


Conclusion: Directly measured free 25-hydroxyvitamin D levels, but not serum total 25-hydroxyvitamin D levels, are different within the first 12 months of estrogen replacement depending on the preparation. However, this difference is transient, in that there were no differences at 36 or 48 months.

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Updated Perspectives on the Role of Estrogens in Skin Aging | CCID

Updated Perspectives on the Role of Estrogens in Skin Aging | CCID

Source : https://doi.org/10.2147/CCID.S333663

For many years, it has been recognized that estrogens are important in the maintenance of human skin. Women seek cosmetic and medical treatments to improve dermal health and physical characteristics...


Conclusion: Especially where skin collagen and elastin profiles are known to follow 17β-estradiol levels during aging and at/after menopause. Finally, the classification of isoflavonoid compounds as endocrine disruptors is unwarranted. In fact, isoflavonoids act as SERMs that bind to ER in the skin to enhance dermal health. Whereas the topical...

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  • 3yr
    Key Points • Source: Clinical, Cosmetic and Investigational Dermatology • Relevance: “The narrative for this overview focuses on updating the factors that influence skin aging and the important role estrogens and selective estrogen receptor Show More