Increased nitrate intake from beetroot juice over 4 weeks affects nitrate metabolism, but not vascular function or blood pressure in older adults with hypertension
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034575/
The decline in vascular function and increase in blood pressure with aging contribute to an increased cardiovascular disease risk. In this randomized placebo-controlled crossover study, we evaluated whether previously reported...
Compared to placebo, plasma and salivary nitrate and nitrite increased at 3H and 4WK POST following nitrate treatment (P < 0.01), suggesting a functioning nitrate-nitrite-NO pathway in the participants of this study. There were no differences between treatments in FBFACh and FBFGTN-area under the curve (AUC) ratios [AUC ratios...
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PFAS and their association with the increased risk of cardiovascular disease in postmenopausal women
Source : https://pubmed.ncbi.nlm.nih.gov/38758093/
Cardiovascular diseases (CVD) are one of the major causes of death globally. In addition to traditional risk factors such as unhealthy lifestyles (smoking, obesity, sedentary) and genetics, common environmental exposures,...
Here, we show that PFOS can be a good predictor of coronary artery disease, while PFOA can be an intermediate predictor of coronary microvascular disease. We also found that the PFAS levels in our study are significantly associated with inflammation-related proteins. Our findings may provide new insight into the potential mechanisms...
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Migraines, vasomotor symptoms, and cardiovascular disease in the Coronary Artery Risk Development in Young Adults study
Source : https://pubmed.ncbi.nlm.nih.gov/38350045/
Migraines and persistent VMS jointly associate with greater risk for CVD and stroke, although risk is attenuated with adjustment for traditional CVD risk factors.
Migraines and persistent VMS jointly associate with greater risk for CVD and stroke, although risk is attenuated with adjustment for traditional CVD risk factors.
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Vasomotor symptoms and cardiovascular health: findings from the SWAN and the MsHeart/MsBrain studies
Source : https://pubmed.ncbi.nlm.nih.gov/37577812/
Vasomotor symptoms (VMS) are often considered the classic menopausal symptom and are experienced by most women during the menopause transition. VMS are well established to be associated with decrements in...
Using a range of methodologies and extensive consideration of confounders, these studies have shown that frequent and/or persistent VMS are associated with adverse CVD risk factor profiles, poorer underlying peripheral vascular and cerebrovascular health, and elevated risk for clinical CVD events. Collectively, the SWAN and MsHeart/MsBrain...
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The Association of Race, Ethnicity, and Socioeconomic Status on the Severity of Menopause Symptoms: a Study of 68,864 Women
Source : https://pubmed.ncbi.nlm.nih.gov/38652870/
Our study suggests that the relationship between race and ethnicity and the severity of menopause symptoms is not solely explained by differences in SES but is itself an independent factor....
The relationship between race/ethnicity and severity of menopause symptoms was not solely explained by differences in socioeconomic status but is itself an independent factor.
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