Insights Into the Genetics of Menopausal Vasomotor Symptoms: Genome-Wide Analyses of Routinely-Collected Primary Care Health Records
Source : https://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-023-01658-w
Vasomotor symptoms (VMS) can often significantly impact women's quality of life at menopause. In vivo studies have shown that increased neurokinin B (NKB) / neurokinin 3 receptor (NK3R) signalling contributes...
In this large study of menopausal VMS derived from primary care health records, researchers demonstrated the potential of routine health care data for deriving phenotypes not available in self-reported study data.
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Veozah (Fezolinetant): a Promising Non‐Hormonal Treatment for Vasomotor Symptoms in Menopause
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551868/
Vasomotor symptoms (VMS) are a common and distressing experience during menopause, affecting a significant portion of women. Hormone therapy (HT) has been the traditional treatment, but its limitations and potential...
Fezolinetant is the first nonhormonal therapy that can cross the blood‐brain barrier to inhibit neurokinin B and alleviate hot flashes in the body. Furthermore, the oral availability of fezolinetant provides a convenient option for menopausal women seeking relief from vasomotor symptoms, contributing to their overall well‐being and...
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Effect of Resistance Training Volume on Body Adiposity, Metabolic Risk, and Inflammation in Postmenopausal and Older Females: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Source : https://www.sciencedirect.com/science/article/pii/S2095254623000972?via=ihub
This meta-analytical study explored the effects of resistance training (RT) volume on body adiposity, metabolic risk, and inflammation in postmenopausal women.
Compared with CG, HVRT protocols elicit greater improvements in metabolic risk and inflammation outcomes than LVRT in overweight/obese postmenopausal and older females.
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Treatment of Urge Incontinence in Postmenopausal Women: a Systematic Review
Source : https://www.pagepressjournals.org/index.php/aiua/article/view/11718
Urinary incontinence and other urinary symptoms tend to be frequent at menopause because of hormonal modifications and aging. Urinary symptoms are associated with the genitourinary syndrome of menopause which is...
At present, a combination of different treatments tailored to the characteristics of the individual patient can be suggested.
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A Systematic Review of Menopause Apps With an Emphasis on Osteoporosis
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542256/
Menopause can significantly hasten bone loss. Mobile phones provide an efficient way to manage, track and understand menopause using apps. A previous review of menopause apps found numerous apps designed...
Existing menopause apps need more input from experts to improve the quality and functionality, using simple language. More emphasis on specific health problems during menopause, including osteoporosis, is required.
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