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Role of Estrogen in the Regulation of Central and Peripheral Energy Homeostasis: From a Menopausal Perspective

Role of Estrogen in the Regulation of Central and Peripheral Energy Homeostasis: From a Menopausal Perspective

Source : https://pubmed.ncbi.nlm.nih.gov/37719789/

Estrogen plays a prominent role in regulating and coordinating energy homeostasis throughout the growth, development, reproduction, and aging of women. Estrogen receptors (ERs) are widely expressed in the brain and...

Cessation of the ovarian function with declined circulating E2 level leads to widespread changes in glucose and lipid metabolism. The adaption of women to menopause is individualized. Initiation of MHT at an early stage of menopause may effectively enhance the metabolic rate, and attenuate the development of obesity, insulin resistance, type...

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Preview of the 2023 North American Menopause Society Annual Meeting

The North American Menopause Society (NAMS) will host its annual meeting at the Marriott Downtown in Philadelphia from Sept. 27 to 30, 2023. The theme of this year’s meeting is Midlife Women’s Health in the Era of Precision Medicine. A vast array of speakers will cover recent clinical research and other content related to menopause and midlife women’s health. 

We will be covering the event for you, so check your email for highlights and a wrap-up of the conference. Click above for an exclusive preview of the event.

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Injection Treatments for Vulvovaginal Atrophy of Menopause: A Systematic Review - Aesthetic Plastic Surgery

Injection Treatments for Vulvovaginal Atrophy of Menopause: A Systematic Review - Aesthetic Plastic Surgery

Source : https://link.springer.com/article/10.1007/s00266-023-03550-5

Background Injection treatments have been proposed as novel treatment options for Vulvovaginal Atrophy of Menopause (VVA) also known as Genitourinary Syndrome of Menopause (GSM). However, to date data about these...

Conclusion: All assessed injection treatments except for MFAT seem to lead to significant improvement in VVA symptoms on validated questionnaires. Further studies are necessary in the field.

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Progestogens for endometrial protection in combined menopausal hormone therapy: A systematic review

Progestogens for endometrial protection in combined menopausal hormone therapy: A systematic review

Source : https://www.sciencedirect.com/science/article/pii/S1521690X23000891?via=ihub

Menopausal women with an intact uterus choosing estrogens for menopausal symptom relief require a progestogen for endometrial protection. The aim of t...

Conclusion: most studies demonstrated endometrial protection for the progestogen dose and time period examined. However, study quality varied which should be taken into account when choosing a combined MHT, especially if off-label-use is chosen.

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Age at Menopause and the Risk of Stroke: Observational and Mendelian Randomization Analysis in 204 244 Postmenopausal Women - PubMed

Age at Menopause and the Risk of Stroke: Observational and Mendelian Randomization Analysis in 204 244 Postmenopausal Women - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/37681566/

Background Observational studies have shown that women with an early menopause are at higher risk of stroke compared with women with a later menopause. However, associations with stroke subtypes are...

Conclusion: In our study, earlier age at menopause was related to a higher risk of stroke. We found no statistically significant association between genetically proxied age at menopause and risk of stroke, suggesting no causal relationship.

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