How menopause reshapes the brain
Source : https://www.nature.com/articles/d41586-023-01474-3
Researchers are starting to learn how the early stages of menopause affect brain health - and what that could mean for treatment. Researchers are starting to learn how the early...
Discussion: Researchers increasingly recognize that menopause and the transition to it, a phase labelled perimenopause, could set the stage for brain health in later life, and there are even hints that it could correlate with the risk of neurodegenerative diseases, such as Alzheimer’s disease.
Impact of Menopause Symptoms on Women in the Workplace
Source : https://www.sciencedirect.com/science/article/abs/pii/S002561962300112X
We conducted a one-time survey study among women aged 45 to 60 years receiving primary care at 1 of 4 Mayo Clinic sites-Rochester, Minnesota; Scottsdale, Arizona; Jacksonville, Florida; and Mayo...
Conclusion: This large cross-sectional study identified a major negative impact of menopause symptoms on work outcomes and the need to improve medical treatment for these women and make the workplace environment more supportive. Additional studies are needed to confirm these findings in larger and more diverse groups of women.
A multicenter, randomized, placebo-controlled study to select the minimum effective dose of estetrol in postmenopausal participants (E4Relief): part 2-vaginal cytology, genitourinary syndrome of menopause, and health-related quality of life - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36809193/
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Conclusion: E4 demonstrated estrogenic effects in the vagina and decreased signs of atrophy. E4 15 mg is a promising treatment option also for important menopausal symptoms other than VMS.
Standard Heart Rate Variability Parameters-Their Within-Session Stability, Reliability, and Sample Size Required to Detect the Minimal Clinically Important Effect
Source : https://www.mdpi.com/2077-0383/12/9/3118
Many intervention studies assume the stability of heart rate variability (HRV) parameters, and their sample sizes are often small, which can significantly affect their conclusions. The aim of this study...
Conclusion: We found significant differences in the mean values of most HRV parameters between measurements during the first 20 min compared with measurements during the last 30 min of recording. Therefore, optimal measurement protocols in a resting sitting position should be performed within the first 20 min or between 20 and 50 min after...
Role of Phytoestrogen in Menopausal Women With Depressive Symptoms: A Consecutive Case Series Study
Introduction During menopause, healthy women experience a diverse aggregate of clinical manifestations and symptoms that relate to hormonal and aging changes. These alterations are strictly associated with psychological disorders, mainly...
Conclusion: Phytoestrogen administration to menopausal women is indicated to reduce depression symptoms. More research in the area is needed to reach definite conclusions.