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Differing effects of oral conjugated equine estrogen and transdermal estradiol on vitamin D metabolism in postmenopausal women: a 4-year longitudinal study - PubMed

Differing effects of oral conjugated equine estrogen and transdermal estradiol on vitamin D metabolism in postmenopausal women: a 4-year longitudinal study - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35969885/

Directly measured free 25-hydroxyvitamin D levels, but not serum total 25-hydroxyvitamin D levels, are different within the first 12 months of estrogen replacement depending on the preparation. However, this difference...


Conclusion: Directly measured free 25-hydroxyvitamin D levels, but not serum total 25-hydroxyvitamin D levels, are different within the first 12 months of estrogen replacement depending on the preparation. However, this difference is transient, in that there were no differences at 36 or 48 months.

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Updated Perspectives on the Role of Estrogens in Skin Aging | CCID

Updated Perspectives on the Role of Estrogens in Skin Aging | CCID

Source : https://doi.org/10.2147/CCID.S333663

For many years, it has been recognized that estrogens are important in the maintenance of human skin. Women seek cosmetic and medical treatments to improve dermal health and physical characteristics...


Conclusion: Especially where skin collagen and elastin profiles are known to follow 17β-estradiol levels during aging and at/after menopause. Finally, the classification of isoflavonoid compounds as endocrine disruptors is unwarranted. In fact, isoflavonoids act as SERMs that bind to ER in the skin to enhance dermal health. Whereas the topical...

  • 3yr
    Key Points • Source: Clinical, Cosmetic and Investigational Dermatology • Relevance: “The narrative for this overview focuses on updating the factors that influence skin aging and the important role estrogens and selective estrogen receptor Show More
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Conclusion: This cohort study found a risk for ENM in women with laparoscopically confirmed endometriosis. These women compared with those without endometriosis may be at a higher risk for shortened reproductive duration, particularly those who were nulliparous or never used oral contraceptives

  • 3yr
    study suggest that women with endometriosis may be at a higher risk for a shortened reproductive duration
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Genitourinary Syndrome of Menopause

Genitourinary Syndrome of Menopause

Source : https://effectivehealthcare.ahrq.gov/products/genitourinary-syndrome/key-questions

Introduction The Patient-Centered Outcomes Research Institute (PCORI) is partnering with the Agency for Healthcare Research and Quality (AHRQ) to develop a systematic evidence review on Genitourinary Syndrome of Menopause. The...


Discussion: The negative effect of GSM on quality of life is substantial; as many as 85% of patients over 40 years of age report vaginal dryness, 29-59% report dyspareunia, 26-77% report vaginal itching and irritation and 40-68% report negative consequences on their sex life, including decreased sexual satisfaction and frequency.

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Menopausal Symptoms and Sleep Quality in Women Aged 40-65 Years

Menopausal Symptoms and Sleep Quality in Women Aged 40-65 Years

Source : https://www.hindawi.com/journals/bmri/2022/2560053/

The study examined the relationship between menopausal symptoms and sleep disturbances and the related influencing factors. Methods . We recruited women aged 40-65 years who attended the menopause clinic at...


Conclusion: Menopausal symptoms are strongly correlated with the degree of sleep disorders. Menopausal syndrome palliation may alleviate the severity of sleep disorders in women.