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Association of adverse pregnancy outcomes and multiple gestation with natural menopause: A population-based cohort study

Association of adverse pregnancy outcomes and multiple gestation with natural menopause: A population-based cohort study

Source : https://www.maturitas.org/article/S0378-5122(22)00219-5/fulltext

Early menopause, the cessation of ovarian function before the age of 45 years, affects approximately 10 % of women [1]. Women who experience early menopause are at increased risk of a nonfatal...


Conclusion: In this large cohort study, several statistically significant associations between APOs and age at natural menopause were observed. A deeper understanding of the relationships among APOs, menopause, and CVD is needed to help identify people at higher risk for early menopause and later CVD.

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History of Previous Midlife Estradiol Treatment Permanently Alters Interactions of Brain Insulin-like Growth Factor-1 Signaling and Hippocampal Estrogen Synthesis to Enhance Cognitive Aging in a Rat Model of Menopause

History of Previous Midlife Estradiol Treatment Permanently Alters Interactions of Brain Insulin-like Growth Factor-1 Signaling and Hippocampal Estrogen Synthesis to Enhance Cognitive Aging in a Rat Model of Menopause

Source : https://www.jneurosci.org/content/42/42/7969

Across species, including humans, elevated levels of brain estrogen receptor (ER) α are associated with enhanced cognitive aging, even in the absence of circulating estrogens. In rodents, short-term estrogen treatment,...


Conclusion: Results indicate that short-term estrogen treatment following midlife loss of ovarian function has long-lasting effects on hippocampal function and memory by dynamically regulating cellular mechanisms that promote activity of ERα in the absence of circulating estrogens. Findings demonstrate how changes in hippocampal ERα...

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Prediction of risk of depressive symptoms in menopausal women based on hot flash and sweating symptoms: a multicentre study

Prediction of risk of depressive symptoms in menopausal women based on hot flash and sweating symptoms: a multicentre study

Source : https://www.tandfonline.com/doi/full/10.2147/CIA.S148688

Abstract The present study aimed to develop a symptom-based (namely, hot flashes and sweating) scoring system for predicting the risk of depressive symptoms in menopausal women via a multicentre cross-sectional...


Discussion: The hot flash and sweating symptom-based scoring system developed to predict the risk of depressive symptoms in menopausal women relies on non-laboratory survey data. The system is simple, practical, and convenient to use.

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Recap of the 2022 North American Menopause Society Annual Meeting

More than 1 million women in the United States experience menopause each year, according to the National Institute on Aging. The North American Menopause Society (NAMS) 2022 Annual Meeting brought together the best and brightest minds in women’s health to discuss what is known about perimenopause, menopause, and postmenopausal health as well as what still needs to be learned.

The four-day meeting covered the treatment of vexing vasomotor symptoms with and without hormones, sleep disorders, and heart and bone health during menopause, with a focus on diversity. Click above for a post-conference wrap-up report.

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Recap of the 2022 North American Menopause Society Annual Meeting

More than 1 million women in the United States experience menopause each year, according to the National Institute on Aging. The North American Menopause Society (NAMS) 2022 Annual Meeting brought together the best and brightest minds in women’s health to discuss what is known about perimenopause, menopause, and postmenopausal health as well as what still needs to be learned.

The four-day meeting covered the treatment of vexing vasomotor symptoms with and without hormones, sleep disorders, and heart and bone health during menopause, with a focus on diversity. Click above for a post-conference wrap-up report.

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