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Did you know? Menopause may amplify the impact of environmental exposures on health. Emerging evidence shows heavy metals can disrupt the oral microbiome, with postmenopausal women exhibiting loss of key microbial species and altered metabolic pathways linked to cardiovascular and metabolic risk.

Could targeting environmental exposures and microbiome health offer new strategies to reduce systemic risks in postmenopausal women?

NCCN Guidelines

Could targeting environmental exposures and microbiome health offer new strategies to reduce systemic risks in postmenopausal women?

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Beyond recurrence detection: Treating the forgotten menopause in endometrial cancer survivors - PubMed

Beyond recurrence detection: Treating the forgotten menopause in endometrial cancer survivors - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41904920/

Endometrial cancer is the most curable gynecological malignancy. Recurrence detection remains central to follow-up; however the management of treatment-induced morbidity remains comparatively underemphasized. As a result, menopausal symptoms remain under-recognized,...

Menopausal symptoms in endometrial cancer survivors remain underrecognized, despite evidence supporting safe hormone therapy in early-stage disease, highlighting the need for personalized, multidisciplinary survivorship care prioritizing quality of life.

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Menopausal hormone therapy and risk of liver cancer in a swedish population-based cohort study - PubMed

Menopausal hormone therapy and risk of liver cancer in a swedish population-based cohort study - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41866298/

MHT in women may decrease the risk of hepatocellular carcinoma, but not intrahepatic cholangiocarcinoma.

Cohort study shows menopausal hormone therapy is associated with reduced hepatocellular carcinoma risk, particularly in older women, with no effect on cholangiocarcinoma, suggesting hormone-related pathways in liver cancer development.

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Association between early menopause and late-life anxiety symptoms among community-dwelling hypertensive women - PubMed

Association between early menopause and late-life anxiety symptoms among community-dwelling hypertensive women - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41819944/

Early menopause is significantly associated with late-life anxiety symptoms in hypertensive women in Central China.

Cross-sectional study found early menopause significantly associated with higher prevalence of late-life anxiety symptoms among hypertensive women, highlighting potential long-term mental health implications of premature menopause.

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SABCS 2025: Practice-Changing Trials and Evolving Standards in Breast Cancer Care

In this SABCS 2025 conference video, Dr. Virginia Kaklamani, Professor of Medicine at UT Health San Antonio and Co-Director of SABCS, discusses key advances shaping contemporary breast cancer care. Highlights include emerging applications of artificial intelligence in breast cancer management, findings from the HER2-CLYMO5 trial supporting chemotherapy de-escalation with tucatinib, and promising phase 3 data evaluating the oral selective estrogen receptor degrader giredestrant.

Dr. Isabel Bedrosian, Professor of Breast Surgical Oncology at MD Anderson Cancer Center, reviews results from the Alliance A11104 trial, which demonstrated that routine preoperative breast MRI did not improve locoregional control or survival in patients with early-stage breast cancer. These findings reinforce evidence-based surgical decision-making and support a more selective approach to preoperative imaging.

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