Essential phospholipids and enzyme-based staging in nonalcoholic fatty liver disease: A call to action - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41358059/
Nonalcoholic fatty liver disease, recently termed metabolic dysfunction-associated steatotic liver disease, affects 25% of adults globally, with a prevalence reaching 93% in obese individuals. The MANPOWER study, a post hoc...
Essential phospholipids improved liver enzymes and ultrasound features in MASLD/NAFLD, while a simple enzyme-based algorithm showed moderate accuracy for NASH detection, supporting noninvasive management and reduced biopsy dependence.
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A scoping review of dietary interventions to treat obesity among Prader-Willi syndrome individuals - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41341915/
Prader-Willi syndrome (PWS) is a genetic disorder resulting from the absence of paternal 15q11-q13 alleles and is clinically characterised by pathological obesity, delayed satiety, hyperphagia, decreased muscle mass, and increased...
Evidence is limited, but ketogenic and multidisciplinary diet–exercise programs aid weight and fat reduction in Prader–Willi syndrome, whereas strict diets face adherence issues; supervised multidisciplinary approaches show best outcomes.
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Effects of Health Qigong Walking Practice on anxiety and serum metabolites in patients with Type 2 Diabetes Mellitus: A randomized controlled trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41176176/
Health Qigong Walking Practice significantly reduces anxiety and improves glucose-lipid metabolism in T2DM patients with anxiety. Its superiority over standard aerobic exercise in glycemic control may be mediated through the...
Qigong walking markedly reduced anxiety and improved glycemic control in T2DM patients beyond aerobic exercise; metabolomics showed shifts in amino-acid and nitrogen pathways, supporting holistic mind-body benefits.
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A Rare Cause of Umbilical Discharge in a Healthy Adult: A Case Report of Patent Urachal Sinus in Primary Care - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41211096/
Umbilical discharge in adults is a rare presentation in primary care and is frequently misdiagnosed as superficial infections, umbilical dermatitis, or abscesses, particularly in individuals with known predisposing factors such...
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Risk of all-cause death and pancreatic events following GLP-1 RA initiation in people with obesity or type 2 diabetes: observations from a federated research network - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41257737/
GLP-1 RA use was associated with substantially reduced all-cause death but a small increased risk of acute pancreatitis, particularly during early treatment. The survival benefit was more pronounced in younger...
GLP-1 RA initiation markedly reduced all-cause mortality but slightly increased early acute pancreatitis risk, without raising chronic pancreatitis or pancreatic cancer, underscoring the need for balanced risk–benefit assessment.
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