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A Narrative Review of Approved and Emerging Anti-Obesity Medications

A Narrative Review of Approved and Emerging Anti-Obesity Medications

Source : https://www.sciencedirect.com/science/article/pii/S1319016423002529

Recently, many drugs have been approved for halting overweight and obesity-few types of research shifted to using Anti-obesity medications (AOM) solel...

The use of AOM increased enormously despite its sometimes-dubious safety and ineffectiveness. The public and medical professionals should be vigilant to the real-world benefits of anti-obesity drugs and their achieved effectiveness with an improved safety profile.

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Compared with CG, HVRT protocols elicit greater improvements in metabolic risk and inflammation outcomes than LVRT in overweight/obese postmenopausal and older females.

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Proportion of Participants With Type 2 Diabetes Achieving a Metabolic Composite Endpoint With Once-Weekly Semaglutide Treatment Versus Comparators: Post Hoc Pooled Analysis From SUSTAIN 1-5, 7-10 and SUSTAIN China

Proportion of Participants With Type 2 Diabetes Achieving a Metabolic Composite Endpoint With Once-Weekly Semaglutide Treatment Versus Comparators: Post Hoc Pooled Analysis From SUSTAIN 1-5, 7-10 and SUSTAIN China

Source : https://pubmed.ncbi.nlm.nih.gov/37822270/

Treatment with OW SC semaglutide versus comparators was associated with increased proportions of participants with T2D meeting the composite metabolic endpoint.

Treatment with OW SC semaglutide versus comparators was associated with increased proportions of participants with T2D meeting the composite metabolic endpoint.

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The findings indicate that among the 4 antiobesity drugs currently available for pediatric use, phentermine-topiramate was the most cost-effective option to treat adolescents with severe obesity.

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Switching from 0.75 mg DG to 0.5 mg SG in patients with T2DM improved glycemic variability, mean glycemic index, and daily variability without increasing the hypoglycemic index. The results suggest that switching to SG may be a useful option in patients experiencing inadequate glycemic control with DG.

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