Obesity Connect
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Did you know? Obesity is a chronic, relapsing neurobiological disease driven by dysregulation of appetite-regulating hormones and energy homeostasis. GLP-1 receptor agonism reduces caloric intake centrally and slows gastric emptying. In the STEP 1 trial, once-weekly semaglutide achieved sustained weight reductions with many patients losing more than 15% of body weight, along with meaningful improvements in cardiometabolic risk factors.

How has your framing of obesity as a chronic disease changed how you discuss treatment goals with patients?

NCCN Guidelines

How has your framing of obesity as a chronic disease changed how you discuss treatment goals with patients?

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1mo
Renal denervation triage tool: a practical approach to the management of resistant hypertension. - PubMed

Renal denervation triage tool: a practical approach to the management of resistant hypertension. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42500615

Explore the RDN triage tool's role in managing resistant hypertension by aiding patient selection and enhancing treatment outcomes, supported by clinical trials and meta-analyses.


Renal denervation is an adjunctive therapy for resistant hypertension, with potential to assist in patient selection and treatment outcomes. Disease Condition: Resistant Hypertension. Specialty Focus: Primary Care.

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1mo
Bridging the gap between policy and practice in adolescent health services: evidence from Indian primary public health centers. - PubMed

Bridging the gap between policy and practice in adolescent health services: evidence from Indian primary public health centers. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42469808

India's adolescent health services face gaps, with only 12.5% of facilities dedicated. Addressing privacy, staff shortages, and leveraging digital health are crucial.


Despite RKSK, only 12.5% of facilities offer adolescent services. Barriers include privacy issues and staff shortages; opportunities lie in digital health and community engagement.

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1mo
Laparoscopic removal of swallowable intragastric balloon and conversion to Roux-en-Y gastric bypass with concurrent hiatoplasty: a case report. - PubMed

Laparoscopic removal of swallowable intragastric balloon and conversion to Roux-en-Y gastric bypass with concurrent hiatoplasty: a case report. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42434064

This case report discusses resolving severe balloon intolerance by identifying hiatal pathology and considering surgical options, highlighting potential interventions for obesity management.


Severe intolerance to swallowable balloons in a 41-year-old man with obesity may indicate hiatal issues. Laparoscopic removal, hiatal repair, and gastric bypass were effective interventions.

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1mo
Rethinking LPCAT3 roles in human disease: broadening perspectives beyond ferroptosis. - PubMed

Rethinking LPCAT3 roles in human disease: broadening perspectives beyond ferroptosis. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42399667

Discover LPCAT3's role in phospholipid remodeling and its impact on diabetes and NAFLD, relevant to primary care.


LPCAT3 remodels phospholipids, impacting autophagy, endoplasmic reticulum homeostasis, and inflammation, relevant to diabetes and NAFLD in primary care.

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