Increased Innate Immune Responses in Adolescents With Obesity and its Relation to Subclinical Cardiovascular Measures: an Exploratory Study
Source : https://pubmed.ncbi.nlm.nih.gov/38741712/
Cardiometabolic risk accrues across the life course and childhood and adolescence are key periods for effective prevention. Obesity is associated with inflammation in adults, but pediatric data are scarce. In...
Monocytes from children and adolescents with severe obesity have a pro-inflammatory state compared to controls of the same age with healthy BMI.
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The Efficacy of Platelet-Rich Plasma Injection Therapy in Obese Versus Non-Obese Patients With Knee Osteoarthritis: a Comparative Study
Source : https://www.mdpi.com/2077-0383/13/9/2590
Background/Objectives: Obesity is a common comorbidity in knee osteoarthritis (KOA) patients. Platelet-Rich Plasma (PRP) injection therapy may mitigate KOA. To further clarify potential patient selection for PRP injection therapy, we...
Patients with obesity benefited from platelet-rich plasma injections who had knee osteoarthritis.
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The Association Between Sleep Duration and Cardiometabolic Risk Among Children and Adolescents in the United States (US): a NHANES Study
Source : https://pubmed.ncbi.nlm.nih.gov/38738838/
Longer sleep duration was associated with lower blood pressure and adiposity measures in children. Improving sleep quality by increasing physical activity and light exposure in childhood may decrease the lifetime...
In logistic regression models, longer sleep duration was associated with lower odds of obesity and overweight status.
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Exploring Post-Treatment Weight Changes in Overweight and Obese Patients With Graves’ Disease: a Retrospective Analysis
Introduction: Graves' disease (GD) is associated with primary hyperthyroidism, leading to weight loss before treatment. During the treatment, weight gain is frequently observed, often surpassing the initial weight loss. This...
After treatment, ≈60% of individuals encountered weight gain, exhibiting a higher prevalence among women and those undergoing definitive treatment modalities.
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Semaglutide and Diuretic Use in Obesity-Related Heart Failure With Preserved Ejection Fraction: a Pooled Analysis of the STEP-HFpEF and STEP-HFpEF-DM Trials
Source : https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehae322/7670783?login=false
AbstractBackground and Aims. In the STEP-HFpEF trial program, treatment with semaglutide resulted in multiple beneficial effects in patients with obesity-r
In obesity-related HF with preserved ejection fraction, semaglutide was effective in multiple domains, regardless of baseline diuretic use/dose, and let to a significant reduction in loop diuretic use over time.
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