https://pubmed.ncbi.nlm.nih.gov/37248954/

Resveratrol shows significant anti-obesity effects on 3T3-L1 adipocytes by reducing fat accumulation, inducing apoptosis, and modulating gene expression, suggesting its potential for obesity treatment and prevention.

https://pubmed.ncbi.nlm.nih.gov/38302593/

New obesity treatments, especially entero-pancreatic hormone-based drugs like GLP-1 RAs, show promising weight loss effects rivaling bariatric surgery, with agents like tirzepatide and retatrutide offering enhanced outcomes.

Easily accessible body circumference markers, especially around the hips and waist, strongly correlate with fat-free mass, offering potential for individualized therapy without specialized equipment, particularly using air displacement methods.

Japan’s culturally aligned, prevention-driven public health strategies effectively reduce childhood obesity, unlike the U.S., where systemic and socioeconomic barriers hinder consistent implementation and impact of obesity prevention programs.

https://pubmed.ncbi.nlm.nih.gov/40003506/

Complementary and alternative medicine, especially acupuncture and yoga, may help reduce adolescent obesity by improving BMI and metabolic markers, though studies are limited by small sample sizes.

https://pubmed.ncbi.nlm.nih.gov/39700320/

Yoga and mindfulness may improve weight-related outcomes in adolescents with obesity, but evidence is limited, low-quality, and inconsistent, with no reported safety data—insufficient for clinical recommendation.

This study investigates how acute high-intensity exercise affects appetite control in individuals with overweight/obesity, with or without type 2 diabetes, comparing morning vs. late afternoon sessions in a randomized crossover trial.

A 24-hour water-only fast increased HGH independently of weight loss. Baseline HGH correlated inversely with cardiometabolic risk factors, and individuals with lower baseline HGH showed greater fasting-induced HGH increases and improved insulin resistance.

Obesity care in primary settings is hindered by bias and stigma. This paper promotes inclusive environments and the 5A model to support respectful, effective weight management counseling by healthcare providers.

This review explores the epigenetic basis of childhood obesity, highlighting methylation risk scores' potential for predicting obesity-related diseases, though clinical implementation remains challenging despite promising research advancements.

This meta-analysis finds absolute neutrophil count (ANC) to be a more reliable marker than neutrophil-to-lymphocyte ratio (NLR) for obesity-related inflammation, showing stronger correlation with BMI and less variability across studies.

Hypothalamic obesity results from multiple factors, including hormonal, behavioral, and metabolic dysfunctions. Evaluating six key domains can aid diagnosis and personalized management, as no single approach fits all patients.

An interdisciplinary approach effectively manages obesity and CVD through nutrition (Mediterranean/DASH diets, plant-based foods), individualized exercise, and behavioral health (mindfulness, stress management, therapy), emphasizing gradual, sustainable lifestyle changes for improved outcomes.

This review explores microneedle (MN) technology for obesity treatment, highlighting its role in drug delivery, adipose tissue modulation, and synergy with iontophoresis or photothermal therapy, while addressing challenges and future prospects.

This review explores AI, particularly ML and DL, in obesity research and management, highlighting risk prediction, personalized treatment, and healthcare improvements while addressing challenges like data quality, ethics, and model interpretability.

This review discusses osteoporosis management after bariatric surgery, emphasizing guidelines, lifestyle interventions, and medications like zoledronic acid and denosumab. More research is needed to validate treatment recommendations and fracture prevention strategies.

Responsive feeding interventions for childhood obesity prevention used limited behavior change techniques (BCTs), with "instruction" and "environment modification" being most effective. Incorporating BCTs and theory ensures replicable, impactful interventions.

Childhood obesity is a rising global epidemic influenced by genetics, genomics, and epigenetics. Advancements in genotyping enable personalized treatment and early screening, highlighting the importance of integrating genetics into clinical practice.

Thyroid dysfunctions increase cardiovascular disease risks, including heart failure, atrial fibrillation, and stroke. Amiodarone use can induce thyroid issues, requiring monitoring. Screening and treatment are essential for CVD patients' health outcomes.