Epigenetics of Childhood Obesity - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39809244/
Future research will undoubtedly discover numerous methylation sites that may be involved in the development of obesity and its comorbidities, especially at a young age. This will contribute to a...
This review explores the epigenetic basis of childhood obesity, highlighting methylation risk scores' potential for predicting obesity-related diseases, though clinical implementation remains challenging despite promising research advancements.
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Neutrophils as indicators of obesity-associated inflammation: A systematic review and meta-analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39610288/
Overall, this meta-analysis demonstrates that ANC is a more reliable and stable parameter than NLR for the assessment of obesity-related inflammation, which offers clinicians a novel tool to assist in...
This meta-analysis finds absolute neutrophil count (ANC) to be a more reliable marker than neutrophil-to-lymphocyte ratio (NLR) for obesity-related inflammation, showing stronger correlation with BMI and less variability across studies.
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The Central Control of Energy Metabolism: Hypothalamic Obesity Is Not One Disease - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39819748/
Hypothalamic obesity is not one disease, but different underlying contributing factors may be present. Consequently, hypothalamic obesity management is not one-size-fits-all but needs to be personalized. In this paper, the...
Hypothalamic obesity results from multiple factors, including hormonal, behavioral, and metabolic dysfunctions. Evaluating six key domains can aid diagnosis and personalized management, as no single approach fits all patients.
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Strategies to Manage Obesity: Lifestyle - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39990756/
The treatment of obesity and cardiovascular disease (CVD) is complex, and a variety of strategies are effective in the lifestyle interventions associated with these disease states. An interdisciplinary approach is...
An interdisciplinary approach effectively manages obesity and CVD through nutrition (Mediterranean/DASH diets, plant-based foods), individualized exercise, and behavioral health (mindfulness, stress management, therapy), emphasizing gradual, sustainable lifestyle changes for improved outcomes.
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Microneedle-Mediated Treatment of Obesity - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40006614/
Obesity has become a major public health threat, as it can cause various complications such as diabetes, cardiovascular disease, sleep apnea, cancer, and osteoarthritis. The primary anti-obesity therapies include dietary...
This review explores microneedle (MN) technology for obesity treatment, highlighting its role in drug delivery, adipose tissue modulation, and synergy with iontophoresis or photothermal therapy, while addressing challenges and future prospects.
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