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Treatment of Eating Disorders: Current Status, Challenges, and Future Directions - PubMed

Treatment of Eating Disorders: Current Status, Challenges, and Future Directions - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38211625/

Specific psychological treatments have demonstrated efficacy and represent the first-line approaches recommended for anorexia nervosa, bulimia nervosa, and binge-eating disorder. Unfortunately, many patients, particularly those with anorexia nervosa, do not...

Psychological treatments are first-line for eating disorders, but efficacy remains limited. Pharmacologic options are scarce. Emerging adaptive treatment designs offer clinical insights and potential models for improved future therapies.

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Assessing the efficacy of tocotrienol-rich fraction vitamin E in obese children with non-alcoholic fatty liver disease: a single-blind, randomized clinical trial - PubMed

Assessing the efficacy of tocotrienol-rich fraction vitamin E in obese children with non-alcoholic fatty liver disease: a single-blind, randomized clinical trial - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/39160468/

The study has been registered with the International Clinical Trial Registry under reference number (NCT05905185) retrospective registration on (15/06/2023).

A study on 29 children with obesity and NAFLD found that vitamin E enriched with tocotrienol (TRF) reduced DNA damage, inflammatory cytokines, and liver markers, suggesting its potential as a safe treatment for NAFLD.

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Effects of Metabolic Dysfunction-Associated Steatotic Liver Disease on Bone Density and Fragility Fractures: Associations and Mechanisms - PubMed

Effects of Metabolic Dysfunction-Associated Steatotic Liver Disease on Bone Density and Fragility Fractures: Associations and Mechanisms - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38740429/

Metabolic dysfunction-associated steatotic liver disease (MASLD) has profound adverse effects on bone health and homeostasis. MASLD appears to be associated with changes in bone mineral density (BMD) and fracture rate....

MASLD impacts bone health, reducing BMD and increasing fragility fractures in adults, especially elderly Asian men, due to disrupted bone remodeling, insulin resistance, inflammation, and comorbidities like obesity and diabetes.

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Diet, exercise, and supplements: what is their role in the management of the metabolic dysfunction-associated steatotic liver disease in children? - PubMed

Diet, exercise, and supplements: what is their role in the management of the metabolic dysfunction-associated steatotic liver disease in children? - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38519764/

Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease (NAFLD), is the main cause of chronic liver disease in children and adolescents. Indeed, epidemiological studies have...

Pediatric MASLD, affecting up to 40% of children with obesity, primarily responds to lifestyle interventions like diet and exercise; studies highlight benefits but lack consensus on optimal approaches, warranting further research.

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Obesity and its impact on female reproductive health: unraveling the connections - PubMed

Obesity and its impact on female reproductive health: unraveling the connections - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38264286/

In the modern era, the escalating global prevalence of obesity has profound implications on female reproductive health. Obesity, transcending mere lifestyle choices, has evolved into a complex disorder affecting physiological...

Obesity significantly impacts female reproductive health, contributing to conditions like PCOS, menstrual disturbances, and infertility. Weight loss strategies and IVF efficacy are influenced by obesity, involving hormonal and inflammatory disruptions.

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