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The emergence of obesity in type 1 diabetes - PubMed

The emergence of obesity in type 1 diabetes - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38092958/

Obesity, a chronic low-grade inflammatory disease represented by multifactorial metabolic dysfunctions, is a significant global health threat for adults and children. The once-held belief that type 1 diabetes is a...

This review discusses the intersection of type 1 diabetes and obesity, highlighting their bidirectional relationship, biopsychosocial impacts, and therapeutic approaches, including exercise, nutrition, pharmacotherapy, and bariatric surgery.

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Appetite- and Weight-Regulating Neuroendocrine Circuitry in Hypothalamic Obesity - PubMed

Appetite- and Weight-Regulating Neuroendocrine Circuitry in Hypothalamic Obesity - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38019584/

Since hypothalamic obesity (HyOb) was first described over 120 years ago by Joseph Babinski and Alfred Fröhlich, advances in molecular genetic laboratory techniques have allowed us to elucidate various components...

This review explores the neuroendocrine physiology of appetite and weight regulation, focusing on hypothalamic obesity (HyOb), its pathophysiology, and the challenges in translating molecular discoveries into effective treatments.

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Interventions to prevent obesity in children aged 5 to 11 years old - PubMed

Interventions to prevent obesity in children aged 5 to 11 years old - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38763517/

The body of evidence in this review demonstrates that a range of school-based 'activity' interventions, alone or in combination with dietary interventions, may have a modest beneficial effect on obesity...

This review assessed interventions to prevent obesity in children, finding that dietary, activity, and combined interventions have minimal or moderate effects on BMI and zBMI, with limited evidence on serious adverse events.

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Innovative Cardiovascular Research Insights at AHA’s 100th Anniversary

At the American Heart Association’s centennial conference, Dr. Amit Khera, Director of Preventive Cardiology and Professor at UT Southwestern Medical Center, and Dr. John L. Sapp, Assistant Dean of Clinical Research at Dalhousie University, presented key findings. Topics included Tirzepatide’s impact on HFpEF and obesity, the comparison of left atrial appendage closure versus anticoagulation for atrial fibrillation, intensive blood pressure control in diabetes, and insights from the VANISH2 trial on ventricular tachycardia. These findings provide healthcare professionals with evidence-based strategies to advance cardiovascular care.

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Effects of Weight Loss on Key Obesity-Related Biomarkers Linked to the Risk of Endometrial Cancer: A Systematic Review and Meta-Analysis - PubMed

Effects of Weight Loss on Key Obesity-Related Biomarkers Linked to the Risk of Endometrial Cancer: A Systematic Review and Meta-Analysis - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38927903/

Endometrial cancer (EC) includes various histologic types, with estrogen-dependent endometrioid carcinoma being the most common. Obesity significantly increases the risk of developing this type, especially in postmenopausal women, due to...

This review analyzes weight loss interventions (bariatric surgery, pharmacotherapy, lifestyle changes) on obesity-related biomarkers in endometrioid EC, finding significant reductions in proinflammatory markers and hormones, but highlighting study limitations and gaps.

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