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Obesity-Related Ciliopathies: Focus on Advances of Biomarkers - PubMed

Obesity-Related Ciliopathies: Focus on Advances of Biomarkers - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/39126056/

Obesity-related ciliopathies, as a group of ciliopathies including Alström Syndrome and Bardet-Biedl Syndrome, exhibit distinct genetic and phenotypic variability. The understanding of these diseases is highly significant for understanding the...

This paper reviews obesity-related ciliopathies, like Alström and Bardet-Biedl syndromes, emphasizing primary cilia’s role, clinical variability, and the need for biomarker research to improve diagnosis, prognosis, and treatment insights.

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Management of cardiovascular risk in patients with metabolic dysfunction-associated steatotic liver disease - PubMed

Management of cardiovascular risk in patients with metabolic dysfunction-associated steatotic liver disease - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38008609/

The novel term Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is proposed to replace non-alcoholic fatty liver disease (NAFLD) to highlight the close association with the metabolic syndrome. MASLD encompasses patients...

MASLD, replacing NAFLD, links liver steatosis to cardiometabolic risks, with CVD as a leading cause of death. Screening via SCORE2, lifestyle changes, statins, and anti-hypertensives are recommended treatments.

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Obesity and its comorbidities, current treatment options and future perspectives: Challenging bariatric surgery? - PubMed

Obesity and its comorbidities, current treatment options and future perspectives: Challenging bariatric surgery? - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/37879540/

Obesity and its comorbidities, including type 2 diabetes mellitus, cardiovascular disease, heart failure and non-alcoholic liver disease are a major health and economic burden with steadily increasing numbers worldwide. The...

The article reviews obesity and its comorbidities, highlighting organ-specific mechanisms, effective treatments like bariatric surgery, emerging pharmacological options, and the potential of targeting the gut-brain axis for future therapies.

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Obesity Management in Adults: A Review - PubMed

Obesity Management in Adults: A Review - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38015216/

Obesity affects approximately 42% of adults in the US. Behavioral interventions can attain approximately 5% to 10% weight loss, GLP-1 agonists and glucose-dependent insulinotropic polypeptide/GLP-1 receptor agonists can attain approximately...

Obesity affects 42% of US adults, increasing health risks. Effective treatments include behavioral interventions, GLP-1 agonists, and bariatric surgery, achieving 5-30% weight loss based on individual needs.

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