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Post metabolic bariatric surgery weight regain: the importance of GLP-1 levels - PubMed

Post metabolic bariatric surgery weight regain: the importance of GLP-1 levels - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38225284/

Weight regain and insufficient weight loss are essential problems after metabolic bariatric surgery (MBS) in people living with obesity. Changes in the level of glucagon-like peptide-1 (GLP-1) secreted from the...

 

This review highlights post-bariatric surgery GLP-1 changes linked to weight loss success and suggests GLP-1 receptor agonists as promising treatments for weight regain or insufficient weight loss after surgery.

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ADA 2025 Highlights: Obesity Therapies, Islet Cell Advances, and Oral GLP-1 Outcomes in T2D

At ADA 2025, Dr. Mark Atkinson (University of Florida Diabetes Institute) highlighted the systemic benefits of obesity-targeted therapies, including cardiometabolic and cognitive improvements, while noting concerns about implementation and potential muscle loss. Emerging advances in stem cell–derived islet transplantation for type 1 diabetes show promise in reducing insulin dependence. Dr. John Buse (University of North Carolina) presented SOUL trial data indicating that oral GLP-1 receptor agonist therapy reduced major adverse cardiovascular events—CV death, nonfatal MI, or stroke—by 14%, with additional reductions in limb complications in high-risk patients with type 2 diabetes.

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Enhancing gut microbiota and microbial function with inulin supplementation in children with obesity - PubMed

Enhancing gut microbiota and microbial function with inulin supplementation in children with obesity - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/39033197/

Inulin supplementation significantly promoted gut bacterial diversity and improved gut microbiota dysbiosis in children with obesity. The modulation of functional pathways by inulin suggests its potential to establish beneficial interactions...

 

Inulin supplementation in children with obesity improved gut microbiota diversity, increased beneficial bacterial populations, and modulated functional pathways, suggesting its potential as a therapeutic strategy for microbiota restoration and metabolic improvement.

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Obesity pharmacotherapy in older adults: a narrative review of evidence - PubMed

Obesity pharmacotherapy in older adults: a narrative review of evidence - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38710803/

The prevalence of obesity in older adults (people aged >60 years) is increasing in line with the demographic shift in global populations. Despite knowledge of obesity-related complications in younger adults...

 

Obesity in older adults poses unique risks, but intentional weight loss—via lifestyle changes and emerging anti-obesity medications—can be safe and effective, improving health while preserving muscle and functional ability.

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Approach to Obesity Treatment in Primary Care: A Review - PubMed

Approach to Obesity Treatment in Primary Care: A Review - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/38466272/

Primary care clinicians play a vital role in the assessment, management, and support of patients with obesity. With careful clinical assessment and shared decision-making, a flexible treatment plan can be...

 

Effective obesity care in primary settings requires integrating lifestyle changes with adjunctive therapies like antiobesity medications or surgery, enabling sustained weight loss and health gains through individualized, evidence-based treatment plans.

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