Pharmacotherapy for Obesity: Moving Towards Efficacy Improvement
Source : https://dmsjournal.biomedcentral.com/articles/10.1186/s13098-023-01233-4
Obesity is a chronic, recurring, progressive disease and a major public health problem associated with several other diseases that lead to disability, morbidity, and mortality. The prevalence of obesity has...
Semaglutide changes the overall landscape of obesity care, as phase 3 studies show a mean weight loss near the 15% threshold and significant proportions of patients with a weight loss of >20%.
Bariatric Surgery in Prospective Obese Living Kidney Donors: Scoping Review and Management Decision Algorithm
Source : https://pubmed.ncbi.nlm.nih.gov/38127433/
BS shows promise with short-term effectiveness and potential long-term outcomes. However, it should not be perceived as a means to expand the donor pool but rather as a personalized approach...
Cost-benefit analysis favors bariatric surgery over nephrectomy in obese donors (cost-benefit ratio: 3.64) when graft survival is equal.
Effect of Carbohydrate Restriction on Body Weight in Overweight and Obese Adults: a Systematic Review and Dose-Response Meta-Analysis of 110 Randomized Controlled Trials
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10731359/
Carbohydrate-restricted diets are one of the most effective dietary interventions for weight loss. However, the optimum carbohydrate intake for implementing the most effective weight-loss interventions is still being discussed. We...
If the goal is to achieve weight loss in the short term, a low-carbohydrate diet could produce a greater weight-loss effect, and it is recommended to keep protein 20%-25% of calorie intake.
Effect of Remotely Supervised Weight Loss and Exercise Training Versus Lifestyle Counseling on Cardiovascular Risk and Clinical Outcomes in Older Adults With Rheumatoid Arthritis: a Randomized Controlled Trial
Source : https://pubmed.ncbi.nlm.nih.gov/38126260/
In older patients with RA and overweight/obesity, 16 weeks of remotely supervised weight loss, aerobic training, and resistance training improve cardiometabolic health, patient-reported outcomes, and disease activity.
The Impact of Early-Stage Chronic Kidney Disease on Weight Loss Outcomes After Gastric Bypass
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687110/
Weight loss achieved through bariatric metabolic surgery was demonstrated to be effective at reversing chronic kidney dysfunction associated with obesity-related glomerulopathy.
After bariatric metabolic surgery, there was a statistically significant reduction in body weight and BMI (P<0.0001).