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Are We Ready to Recommend Capsaicin for Disorders Other Than Neuropathic Pain?

Are We Ready to Recommend Capsaicin for Disorders Other Than Neuropathic Pain?

Source : https://www.mdpi.com/2072-6643/15/20/4469

Capsaicin, a lipophilic, volatile compound, is responsible for the pungent properties of chili peppers. In recent years, a significant increase in investigations into its properties has allowed the production of...

Type 2 diabetes and dyslipidemia are closely linked to obesity and, consequently, could be beneficiated by capsaicin supplementation.

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2yr
Effect of Long-Acting Versus Short-Acting Glucagon-Like Peptide-1 Receptor Agonists on Improving Body Weight and Related Metabolic Parameters in Type 2 Diabetes: a Head-to-Head Meta-Analysis

Effect of Long-Acting Versus Short-Acting Glucagon-Like Peptide-1 Receptor Agonists on Improving Body Weight and Related Metabolic Parameters in Type 2 Diabetes: a Head-to-Head Meta-Analysis

Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615555/

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) showed great value in treating nonalcoholic fatty liver disease (NAFLD).

Long-acting GLP-1RAs may be more promise than short-acting GLP-1RAs in improving weight and related metabolic parameters.

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Obesity treatment resources

A number of organizations recognize obesity as a chronic, relapsing, progressive disease, yet only a small percentage of patients can achieve their goals and maintain weight loss. Comprehensive care for obesity may involve energy deficit meal plans, physical activity, behavioral modification, consideration of circadian rhythms, and anti-obesity medications. However, providers may have limited time to engage in these and many report the need for more training.

What percent of your obese and overweight patients mention efforts to lose weight?
What resources (for patients or providers) have you found particularly useful in helping patients lose weight and maintain weight loss — or what additional ones would you like to see?

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Association Between Childhood Obesity and Infertility in Later Life: A Systematic Review of Cohort Studies

Association Between Childhood Obesity and Infertility in Later Life: A Systematic Review of Cohort Studies

Source : https://bmcendocrdisord.biomedcentral.com/articles/10.1186/s12902-023-01490-4

Background The global prevalence of childhood obesity has exhibited a troubling surge in recent years. Due to the raised questions regarding its potential correlation with infertility in adulthood, this systematic...

The evidence suggests a positive association between childhood obesity with infertility indicators in later life. Childhood weight reduction strategies are suggested to be implemented in societies in order to reduce infertility rates in later life.

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2yr
Endocrine, Genetic, and Microbiome Nexus of Obesity and Potential Role of Postbiotics: A Narrative Review

Endocrine, Genetic, and Microbiome Nexus of Obesity and Potential Role of Postbiotics: A Narrative Review

Source : https://link.springer.com/article/10.1007/s40519-023-01593-w

Obesity is a public health crisis, presenting a huge burden on health care and the economic system in both developed and developing countries. According to the WHO's latest report on...

Postbiotics such as the SCFAs suppress obesity by regulating metabolic hormones such as GLP-1, and PPY thus reducing feed intake and suppressing appetite. Furthermore, muramyl di-peptides, bacteriocins, and LPS have been tested against obesity and yielded promising results in both human and mice studies.