The Relation Between Excess Adiposity and Breast Cancer in Women: Clinical Implications and Management
Source : https://www.sciencedirect.com/science/article/pii/S1040842823003013?via=ihub
Breast cancer (BC) is the most common cancer in women. While the combination of improved screening, earlier detection, and advances in therapeutics ha...
Weight gain prevention and weight loss interventions should ideally be seamlessly included in the management of BC to provide a holistic, individualized approach to improve health and survival in this population.
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Semaglutide and Tirzepatide Reduce Alcohol Consumption in Individuals With Obesity
Source : https://www.nature.com/articles/s41598-023-48267-2
Alcohol Use Disorder (AUD) contributes significantly to global mortality. GLP-1 (Glucagon-like peptide-1) and GLP-1/GIP (Glucose-dependent Insulinotropic Polypeptide) agonists, FDA-approved for managing type 2 diabetes and obesity, where the former has...
Researchers observed a reduction in average number of drinks, binge drinking, AUDIT score, and the sedative/stimulating effects of alcohol in individuals taking semaglutide or tirzepatide.
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The Effect of Acarbose on Lipid Profiles in Adults: a Systematic Review and Meta-Analysis of Randomized Clinical Trials
Source : https://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-023-00706-6
Dyslipidemia, characterized by elevated levels of triglycerides (TG), low-density lipoprotein (LDL), total cholesterol (TC), and reduced levels of high-density lipoprotein (HDL), is a major risk factor for cardiovascular diseases (CVD)....
The findings of this study suggest that acarbose can reduce serum levels of TG and TC; however, no significant effects were observed on LDL or HDL levels.
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Weight Management Interventions for Adults With Idiopathic Intracranial Hypertension
Source : https://n.neurology.org/content/101/21/e2138.long
Idiopathic intracranial hypertension (IIH) is associated with obesity; however, there is a lack of clinical consensus on how to manage weight in IIH. The aim of this systematic review was...
The biological drivers of obesity may explain why short-term weight management interventions are often insufficient for long-term disease remission. The hierarchy of effect in weight loss methods seems to be analogous to the reduction of ICP, with bariatric surgery having the most robust evidence for effective treatment of obesity in the IIH...
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Researchers review various high-impact studies that link epigenetics with metabolic syndrome by comparing each study population, methylation effects, and strengths and weaknesses of each research.
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