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Relationship between perioperative semaglutide use and residual gastric content: A retrospective analysis of patients undergoing elective upper endoscopy

Relationship between perioperative semaglutide use and residual gastric content: A retrospective analysis of patients undergoing elective upper endoscopy

Source : https://www.sciencedirect.com/science/article/abs/pii/S0952818023000417?via=ihub

Semaglutide, a GLP-1 agonist, has been associated with delayed gastric emptying. * 5.1% of patients not using semaglutide had increased residual gastric content (RGC). * 24.2% of patients taking semaglutide...



Conclusions: Relationship between perioperative semaglutide use and residual gastric content: A retrospective analysis of patients undergoing elective upper endoscopy.

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Conclusions: BE ACTIVE is a virtual, pragmatic randomized clinical trial powered to demonstrate whether gamification, financial incentives, or both are superior to attention control in increasing physical activity. Its results will have important implications for strategies to promote physical activity in patients with or at risk for ASCVD,...

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Once-weekly semaglutide use in patients with type 2 diabetes: results from the SURE France multicentre, prospective, observational study - PubMed

Once-weekly semaglutide use in patients with type 2 diabetes: results from the SURE France multicentre, prospective, observational study - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36869853/

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Conclusions: These results support the benefits of semaglutide in a real-world setting in adults with T2D in France demonstrating a significant reduction in HbA1c and body weight.

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Systematic investigation of the underlying mechanisms of GLP-1 receptor agonists to prevent myocardial infarction in patients with type 2 diabetes mellitus using network pharmacology

Systematic investigation of the underlying mechanisms of GLP-1 receptor agonists to prevent myocardial infarction in patients with type 2 diabetes mellitus using network pharmacology

Source : https://www.frontiersin.org/articles/10.3389/fphar.2023.1125753/full

Background: Several clinical trials have demonstrated that glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) reduce the incidence of non-fatal myocardial infarction (MI) in patients with type 2 diabetes mellitus (T2DM). However,...



Conclusion: GLP-1RAs exert multi-dimensional effects on reducing the occurrence of MI in T2DM patients by interfering with targets, biological processes, and cellular signaling pathways related to atheromatous plaque, myocardial remodeling, and thrombosis.

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Pharmacological Support for the Treatment of Obesity-Present and Future - PubMed

Pharmacological Support for the Treatment of Obesity-Present and Future - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/36767008/

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Relevance: The presented paper is an overview of the studies related to both drugs currently used in the pharmacotherapy of obesity and those undergoing clinical trials, taking into account the individual approach to the patient.

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