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Personalized Nutrition Strategies for Patients in the Intensive Care Unit: A Narrative Review on the Future of Critical Care Nutrition - PubMed

Personalized Nutrition Strategies for Patients in the Intensive Care Unit: A Narrative Review on the Future of Critical Care Nutrition - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40431399/

Introduction: Critically ill patients in intensive care units (ICUs) are at high risk of malnutrition, which can result in muscle atrophy, polyneuropathy, increased mortality, or prolonged hospitalizations with complications and...

Review highlights importance of early, personalized ICU nutrition using enteral feeding, adequate protein, and AI/metabolomics integration to improve outcomes, reduce complications, and enable precise, multidisciplinary nutritional care.

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Did you know? Childhood obesity disrupts multiple endocrine pathways, leading to insulin resistance, hormonal imbalances, and increased risk of early-onset metabolic and cardiovascular complications. These changes can also impact growth, puberty, and long-term health trajectories.

Could early endocrine-focused interventions in obesity help prevent long-term metabolic and cardiovascular disease progression?

 NCCN Guidelines

Could early endocrine-focused interventions in obesity help prevent long-term metabolic and cardiovascular disease progression?

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Obesity accelerates cardiovascular ageing - PubMed

Obesity accelerates cardiovascular ageing - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40197620/

A global obesity pandemic, coupled with an increasingly ageing population, is exacerbating the burden of cardiovascular disease. Indeed, clinical and experimental evidence underscores a potential connection between obesity and ageing...

Obesity accelerates cardiovascular aging through shared mechanisms like inflammation and mitochondrial dysfunction; weight reduction and metabolic therapies may counteract these processes, reducing cardiovascular disease risk and improving longevity.

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Obesity-related TyG indices, reflecting insulin resistance, were linked to higher risk of retinal arteriosclerosis. Findings highlight how metabolic dysfunction and poor cardiovascular health contribute to early microvascular injury, reinforcing the need for integrated risk assessment.

Assess metabolic risk beyond BMI

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Lipodystrophy: an uncommon cause of insulin resistance and young-onset diabetes - PubMed

Lipodystrophy: an uncommon cause of insulin resistance and young-onset diabetes - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41948357/

Insulin resistance due to lipodystrophy syndromes is an uncommon but important cause of diabetes. It is often overlooked due to limited awareness. Standard glucose-lowering therapies often fail to achieve durable...

Lipodystrophy is a rare cause of insulin resistance and early diabetes, often misdiagnosed. Genetic causes like SHORT syndrome should be suspected in lean patients with atypical features and poor response to standard therapies.

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