Semaglutide and Tirzepatide Reduce Alcohol Consumption in Individuals With Obesity
Source : https://www.nature.com/articles/s41598-023-48267-2
Alcohol Use Disorder (AUD) contributes significantly to global mortality. GLP-1 (Glucagon-like peptide-1) and GLP-1/GIP (Glucose-dependent Insulinotropic Polypeptide) agonists, FDA-approved for managing type 2 diabetes and obesity, where the former has...
Researchers observed a reduction in average number of drinks, binge drinking, AUDIT score, and the sedative/stimulating effects of alcohol in individuals taking semaglutide or tirzepatide.
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The Effect of Acarbose on Lipid Profiles in Adults: a Systematic Review and Meta-Analysis of Randomized Clinical Trials
Source : https://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-023-00706-6
Dyslipidemia, characterized by elevated levels of triglycerides (TG), low-density lipoprotein (LDL), total cholesterol (TC), and reduced levels of high-density lipoprotein (HDL), is a major risk factor for cardiovascular diseases (CVD)....
The findings of this study suggest that acarbose can reduce serum levels of TG and TC; however, no significant effects were observed on LDL or HDL levels.
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Weight Management Interventions for Adults With Idiopathic Intracranial Hypertension
Source : https://n.neurology.org/content/101/21/e2138.long
Idiopathic intracranial hypertension (IIH) is associated with obesity; however, there is a lack of clinical consensus on how to manage weight in IIH. The aim of this systematic review was...
The biological drivers of obesity may explain why short-term weight management interventions are often insufficient for long-term disease remission. The hierarchy of effect in weight loss methods seems to be analogous to the reduction of ICP, with bariatric surgery having the most robust evidence for effective treatment of obesity in the IIH...
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Researchers review various high-impact studies that link epigenetics with metabolic syndrome by comparing each study population, methylation effects, and strengths and weaknesses of each research.
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Irisin and Cardiometabolic Disorders in Obesity: a Systematic Review
Source : https://www.hindawi.com/journals/iji/2023/5810157/
Overweight and obesity are global health issues, impacting a significant portion of young adults. Obesity is a complex condition influenced by genetics and environmental factors, leading to increased susceptibility to...
The review suggests that irisin plays a significant role as both a preventive measure and a biomarker for comorbidities linked to obesity and cardiometabolic disorders.
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