A 12-month RCT will assess if adding group-based nutritional education to standard care improves HbA1c in T2D patients. Covering shopping habits, plate planning, and hunger cues, the program targets glycemic control and broader metabolic outcomes.
Is GLP-1 receptor agonist therapy safe for patients with intraductal papillary mucinous neoplasm? - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41100817/
Glucagon-like peptide-1 receptor agonists are increasingly used in the management of obesity and diabetes. Their potential risks, however, particularly regarding pancreatitis and pancreatic cancer, remain contentious. Despite numerous studies and...
Costs of mental health care resource use in people with obesity: A systematic review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41061006/
Our findings suggest that people with obesity incur substantial costs related to the use of mental health care, yet less than half of the included COI studies reported mental health...
This systematic review highlights substantial but inconsistently reported mental health care costs among individuals with obesity, emphasizing the need for clearer cost attribution and integrated economic evaluation of obesity–mental health comorbidity.
Obesity: Prevalence, causes, consequences, management, preventive strategies and future research directions - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/41041606/
Obesity has emerged as one of the most pressing global public health challenges of the 21st century. Obesity has reached epidemic proportions worldwide, with over 1 billion people classified as...
This comprehensive review examines global obesity trends, underlying genetic, behavioral, and environmental causes, and related non-communicable diseases, emphasizing evidence-based management, prevention strategies, and urgent multisectoral actions to mitigate the growing global obesity epidemic.
Obesity disrupts endocrine health through insulin resistance, chronic inflammation, and altered adipokine signaling. This narrative review explores how different dietary patterns influence hormonal balance in men and women.
Highlights:
- In men, obesity is linked to decreased testosterone, reduced thyroid function, possibly reflecting thyroid hormone resistance, and elevated cortisol
- In women, it increases risks for PCOS, infertility, and androgen excess
- Calorie restriction, low-carbohydrate diets, Mediterranean, and plant-based patterns show hormonal benefits
- Hormonal effects of dietary changes are often sex-specific
What sets this study apart:
Unlike conventional reviews that focus on single nutrients, this synthesis examines whole dietary patterns and their interaction with sex-specific hormonal physiology. It emphasizes the importance of individualized nutrition plans based on reproductive and metabolic profiles, underscoring that one-size-fits-all approaches are inadequate for endocrine health.
Limitations:
As a narrative review, conclusions are drawn from existing literature rather than new clinical data. Long-term outcomes and sustainability of restrictive diets, such as ketogenic or very low-carbohydrate regimens, remain underexplored.
What role does gender play in how dietary choices influence endocrine health?

