Obesity pharmacotherapy in older adults: a narrative review of evidence - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38710803/
The prevalence of obesity in older adults (people aged >60 years) is increasing in line with the demographic shift in global populations. Despite knowledge of obesity-related complications in younger adults...
Obesity in older adults poses unique risks, but intentional weight loss—via lifestyle changes and emerging anti-obesity medications—can be safe and effective, improving health while preserving muscle and functional ability.
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Approach to Obesity Treatment in Primary Care: A Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38466272/
Primary care clinicians play a vital role in the assessment, management, and support of patients with obesity. With careful clinical assessment and shared decision-making, a flexible treatment plan can be...
Effective obesity care in primary settings requires integrating lifestyle changes with adjunctive therapies like antiobesity medications or surgery, enabling sustained weight loss and health gains through individualized, evidence-based treatment plans.
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Exercise as a Therapeutic Strategy for Obesity: Central and Peripheral Mechanisms - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39590824/
Obesity is a complex, multifactorial condition involving excessive fat accumulation due to an imbalance between energy intake and expenditure, with its global prevalence steadily rising. This condition significantly increases the...
Exercise combats obesity by modulating central nervous system functions and enhancing peripheral metabolic processes, promoting fat oxidation and energy balance; deeper insight into these interactions can improve obesity management strategies.
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Comparative efficacy of exercise, diet and/or pharmacological interventions on BMI, ovulation, and hormonal profile in reproductive-aged women with overweight or obesity: a systematic review and network meta-analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38627233/
Overall, the findings of this network meta-analysis indicate that the combination of exercise, diet, and pharmacological interventions is effective for weight loss, improving ovulation, and normalizing the androgen levels of...
Combining exercise, diet, and pharmacological interventions effectively reduces BMI, improves ovulation, and normalizes hormones in overweight women, supporting a comprehensive approach to enhance fertility outcomes.
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Emerging pharmacotherapies for obesity: A systematic review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39952695/
The history of antiobesity pharmacotherapies is marked by disappointments, often entangled with societal pressure promoting weight loss and the prevailing conviction that excess body weight signifies a lack of willpower....
This review highlights emerging antiobesity drugs, particularly incretin-based therapies, showing promising weight loss results in phase 2/3 trials, with a need for long-term safety, efficacy, and broader population studies.
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