Key Gaps in the Prevention and Treatment of Obesity in Children and Adolescents: A Critical Appraisal of Clinical Guidelines - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40150629/
Standardizing BMI cut-off points and defining age groups across CPGs would improve consistency and comparability in the diagnosis, prevention, and treatment of childhood obesity. Tailoring recommendations for diet, physical activity,...
Current childhood obesity guidelines lack age-specific recommendations and standardization, especially in BMI criteria, dietary details, and parental roles. Enhancing precision and updating treatment options are crucial for effective interventions.
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An orally active carbon monoxide-releasing molecule enhances beneficial gut microbial species to combat obesity in mice - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38608580/
Carbon monoxide (CO), a gaseous signaling molecule, has shown promise in preventing body weight gain and metabolic dysfunction induced by high fat diet (HFD), but the mechanisms underlying these effects...
Carbon monoxide delivered via CORM-401 reshapes gut microbiota disrupted by a high-fat diet, notably restoring Akkermansia muciniphila, normalizing metabolites, improving gut health, and mitigating inflammation and metabolic dysfunction in mice.
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Interventions to prevent obesity in children aged 12 to 18 years old - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38763518/
The evidence demonstrates that dietary interventions may have little to no effect on obesity in adolescents. There is low-certainty evidence that activity interventions may have a small beneficial effect on...
Obesity prevention interventions in adolescents show little to no impact from diet changes, minor benefits from activity programs, and negligible effects from combined approaches; further large-scale, rigorous studies are needed.
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Interventions to prevent obesity in children aged 5 to 11 years old - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38763517/
The body of evidence in this review demonstrates that a range of school-based 'activity' interventions, alone or in combination with dietary interventions, may have a modest beneficial effect on obesity...
School-based activity interventions, alone or combined with diet changes, modestly reduce childhood obesity short- and medium-term; dietary-only interventions show little effect. Evidence on serious adverse events and health inequalities remains limited.
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The anti-obesity effects of resveratrol on the 3T3-L1 adipocytes - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37248954/
Obesity is a severe health problem worldwide due to its association with various adverse health consequences. The present study aims to evaluate the anti-obesity effects of resveratrol, as a natural...
https://pubmed.ncbi.nlm.nih.gov/37248954/
Resveratrol shows significant anti-obesity effects on 3T3-L1 adipocytes by reducing fat accumulation, inducing apoptosis, and modulating gene expression, suggesting its potential for obesity treatment and prevention.
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