Comparison of Dolutegravir + Lamivudine and Bictegravir/Emtricitabine/Tenofovir Alafenamide in Antiretroviral Therapy-Naive Patients Infected With HIV: Preliminary Results From Clinical Practice
Source : https://pubmed.ncbi.nlm.nih.gov/37927079/
Both optimization strategies showed high tolerability in antiretroviral therapy-naive patients, with no differences in virological efficacy; however, BIC/FTC/TAF may be related to the risk of weight gain risk. Further research...
After 48 weeks, no differences in virologic/immunologic efficacy was seen with patients taking DTG/3TC and BIC/FTC/TAF. However, compared with DTG/3TC, combination BIC/FTC/TAF may lead to greater weight gain.
Immunological Responses in SARS-CoV-2 and HIV Co-Infection Versus SARS-CoV-2 Mono-Infection: Case Report of the Interplay Between SARS-CoV-2 and HIV
Source : https://aacijournal.biomedcentral.com/articles/10.1186/s13223-023-00846-8
There is an urgent need to understand the interplay between SARS-CoV-2 and HIV to inform risk-mitigation approaches for HIV-infected individuals. Objectives We conclude that people living with HIV (PLWH) who...
HIV-associated immune dysregulation in viremic individuals may negatively impact vaccine-induced cellular immunity.
Investigating Coping and Stigma in People Living With HIV Through Narrative Medicine in the Italian Multicentre Non-Interventional Study DIAMANTE
Source : https://www.nature.com/articles/s41598-023-44768-2
Antiretroviral therapy (ART) significantly reduced Human Immunodeficiency Virus (HIV) morbidity and mortality; nevertheless, stigma still characterises the living with this condition. This study explored patients' coping experience by integrating narrative...
Treatment plays a crucial role in reassuring patients about their health status, their risk of death, and the risk of being no longer infectious for their partners. The relationship with the treating clinician was perceived to be pivotal even at the first visit.
Integrating Long-Acting Injectable Treatment to Improve Medication Adherence Among Persons Living With HIV and Opioid Use Disorder: Study Protocol
Source : https://ascpjournal.biomedcentral.com/articles/10.1186/s13722-023-00418-6
Oral antiretroviral therapy (ART) has been effective at reducing mortality rates of people with HIV. However, despite its effectiveness, people who use drugs face barriers to maintaining ART adherence. Receipt...
This work has the potential to improve the treatment and prevention of HIV infection among a population where substance use is a significant contributing factor, by integrating treatment for opioid use disorder and HIV infection.
Second-generation integrase strand transfer inhibitor-based first-line antiretroviral therapy for most people living with HIV is also applicable to those harboring E157Q.