How Does Intersectionality Impact the Quality of Healthcare Services for Black Women Living With HIV?
Source : https://pubmed.ncbi.nlm.nih.gov/38194323/
Women with HIV are affected more than men by intersecting discriminations. For Black women, additional discrimination can have a detrimental effect on their HIV care. An extended literature review of...
Although Black women with HIV infection reported barriers to health care because of intersectionality, older women who felt confident in their self-identity were more able to cope with issues around this.
A Detailed Characterization of Drug Resistance During Darunavir/Ritonavir Monotherapy Highlights a High Barrier to the Emergence of Resistance Mutations in Protease But Identifies Alternative Pathways of Resistance
Source : https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkad386/7503104?login=false
Maintenance monotherapy with ritonavir-boosted darunavir has yielded variable outcomes and is not recommended.
These findings align with published data from a similar population, indicating a heightened risk of viremia among individuals receiving ritonavir-boosted darunavir monotherapy.
Incidence of Hyperlipidemia Among Adults Initiating Antiretroviral Therapy in the HIV Outpatient Study (HOPS), USA, 2007-2021
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10703529/
Current U.S. guidelines recommend integrase strand transfer inhibitor (INSTI)-based antiretroviral therapy (ART) as initial treatment for people with HIV (PWH). We assessed long-term effects of INSTI use on lipid profiles...
People living with HIV infection (PWH) and naïve to antiretroviral therapy receiving routine care with normal lipid profiles had lower rates of incident hyperlipidemia after initiating a RAL-based regimen than a PI-based regimen.
Weight Loss Associated With Semaglutide Treatment Among People With HIV
We identified adult PWH who initiated semaglutide between 2018 and 2022 and with at least 2 weight measurements. The primary outcome was within-person bodyweight change in kilograms at 1 year....
Treatment with semaglutide was associated with an average weight loss of 6.47 kg at 1 year and with a reduction in HbA1c of 1.07% at 1 year among the 157 people with HIV infection with a postindex HbA1c value.
Impact of Screening Programme to Prevent Anal Cancer in High-Risk Patients With HIV
Source : https://pubmed.ncbi.nlm.nih.gov/38031816/
Macroscopic high-grade dysplasia lesions are associated with a higher risk of developing anal cancer.
Among patients strictly adherent to the screening program, researchers did not report any AIN or anal cancer, but they also did not observe any significant reduction in the risk of anal cancer, AIN3, high-grade dysplasia, or any AIN lesions compared with nonadherent patients.