Admission Hyperglycemia as a Predictor of COVID-19 Pneumonia, Cytokine Release Syndrome Progression, and Clinical Outcomes in a Tertiary Care Hospital
Introduction Diabetes and coronavirus disease 2019 (COVID-19) are interrelated. The presence of hyperglycemia per se during COVID-19 infection regardless of diabetes status has been associated with poor prognosis and increased...
Conclusions: Admission hyperglycemia was associated with an increased risk of progression to critical condition in patients hospitalized with COVID-19 independent of the history of diabetes. Therefore, it should not be overlooked but instead should be detected and appropriately treated to improve outcomes. In addition, post-COVID-19 care should...
New COVID-19 Rapid-test Technology Performs PCR Faster than Similar Tests on the Market
Newswise - New York, NY-July 25, 2022-For more than 30 years, polymerase chain reaction (PCR) has been the gold standard in molecular diagnostic testing, detecting genetic material, such as those...
Sample-to-result workflow of RT-qPCR for rapid detection of SARS-CoV-2, including simple extraction-free sample preparation using a custom cartridge. Results are achieved in 23 minutes of thermocycling, facilitated by plasmonic heating of gold nanoparticles and multiplexed fluorescence monitoring in real-time.
Acute and post-acute COVID-19 presentations in athletes: a systematic review and meta-analysis
Source : https://dx.doi.org/10.1136/bjsports-2022-105583
Objective To describe acute/postacute COVID-19 presentations in athletes. Design Systematic review and meta-analysis. Data sources The search was conducted in four databases (MEDLINE, EMBASE, SCOPUS, SPORTDiscus) and restricted to studies...
Conclusion: This broad characterisation of COVID-19 presentations in athletes indicates that ~94% exhibited mild or no acute symptoms. The available evidence did not confirm a causal relationship between COVID-19 and myocardial involvement. A small proportion of athletes experienced persistent symptoms while recovering from infection, which...
Rapid Diagnostic Testing for Response to the Monkeypox Outbreak ..
Source : https://www.cdc.gov/mmwr/volumes/71/wr/mm7128e1.htm?s_cid=mm7128e1_w
On July 8, 2022, this report was posted online as an MMWR Early Release. Tricia A. Aden 1; Patricia Blevins, MPH 1; Shannon Whitman York, PhD 1; Stacy Rager 1;...
Summary:
What is already known on this topic?
The Laboratory Response Network (LRN) includes U.S. laboratories validated to perform the non-variola Orthopoxvirus (NVO) assay.
What is added by this report?
During May 17–June 30, 2022, LRN laboratories tested 2,009 specimens from patients with suspected monkeypox. Among these, 730...
Homogeneous surrogate virus neutralization assay to rapidly assess neutralization activity of anti-SARS-CoV-2 antibodies - Nature Communications
Source : https://www.nature.com/articles/s41467-022-31300-9
The COVID-19 pandemic triggered the development of numerous diagnostic tools to monitor infection and to determine immune response. Although assays to measure binding antibodies against SARS-CoV-2 are widely available, more...
The results obtained with our assay and other neutralization assays are comparable but with significantly shorter preparation and run time for Neu-SATiN. As the assay is modular, we further demonstrate that Neu-SATiN enables rapid assessment of the effectiveness of vaccines and level of protection against existing SARS-CoV-2 variants of concern...