Blood and Urine Biomarkers Predicting Worsening Kidney Function in Patients with Type 2 Diabetes Post-Acute Coronary Syndrome: An Analysis from the EXAMINE Trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34872085/
doi: 10.1159/000519436. Online ahead of print. 1 Centre D'Investigation Clinique-Plurithématique Inserm CIC-P 1433, Inserm U1116, CHRU Nancy Hopitaux de Brabois, F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Université de Lorraine,...
Conclusion: Blood KIM-1 was the biomarker with the strongest association with WKF. The occurrence of WKF was independently associated with a higher risk of subsequent cardiovascular events and mortality.
Odds of Testing Positive for SARS-CoV-2 Following Receipt of 3 vs 2 Doses of the BNT162b2 mRNA Vaccine - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34846533/
Previous studies have demonstrated that vaccine-derived protection against SARS-CoV-2 wanes over time. In this case-control analysis, we showed an association between receipt of the booster dose and a reduction in...
Conclusion and relevance: Previous studies have demonstrated that vaccine-derived protection against SARS-CoV-2 wanes over time. In this case-control analysis, we showed an association between receipt of the booster dose and a reduction in the odds of testing positive for SARS-CoV-2, potentially counteracting waning immunity in the short term....
Exposure to Harmless Coronaviruses Boosts SARS-CoV-2 Immunity
Source : https://www.media.uzh.ch/en/Press-Releases/2021/SARS-CoV-2-Immunity.html
Antibody responce againgst SARS-CoV-2 The population's immunity to SARS-CoV-2, achieved either through infection or vaccination, is crucial to overcome the COVID-19 pandemic. A team of researchers led by the University...
ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome
Source : https://www.science.org/doi/10.1126/sciadv.abl8213
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These data confirm that PF4 is capable of forming stable complexes with clinically relevant adenoviruses, an important step in unraveling the mechanisms underlying TTS.
The primary outcome was the reciprocal of neutralizing antibody titers against a live Wuhan strain (eAppendix in the Supplement). Secondary outcomes included IgG antibodies to the spike protein and receptor-binding domain (RBD) using a multiplex assay (V-PLEX COVID-19 Coronavirus Panel 2 [IgG] Kit, Meso Scale Diagnostics); antibodies to spike...