Focus on Infectious Disease
  • Saved

Key Points: The receptor binding domain (RBD) of SARS-CoV-2 bears sequence and overall ABO blood binding similarity with human galectins. SARS-CoV-2 preferentially infects blood group A cells, providing a direct link between blood group A expression and increased infection.

  • Saved

Current research remains conflicted concerning psychiatric ED admissions during COVID-19, with some stating an increase and others finding a decrease. Our data showed a significant statistical increase in the mean number of psychosis cases when comparing pre-pandemic and pandemic admissions. These findings help add pertinent data to...

  • Saved
The Radiological Spectrum of Rhino-Oculo-Cerebral Mucormycosis

The Radiological Spectrum of Rhino-Oculo-Cerebral Mucormycosis

Source : https://www.cureus.com/articles/157223-the-radiological-spectrum-of-rhino-oculo-cerebral-mucormycosis

Aim We aim to study the spectrum of imaging findings in patients with rhino-oculo-cerebral mucormycosis (ROCM). Materials and methods This retrospective descriptive study was performed in histopathologically confirmed cases of...

ROCM is a life-threatening invasive fungal infection, especially in an immunocompromised state. ROCM is characterized by a variety of imaging abnormalities on CT and MRI, although nonspecific. Imaging aids in suspicion or early diagnosis in appropriate clinical contexts, particularly in an immunocompromised state, and in determining the...

  • Saved
Evaluation and Determination of Quantitative Hepatitis B Surface Antigen Diagnostic Performance in Chronic Hepatitis B Virus-Infected Patients

Evaluation and Determination of Quantitative Hepatitis B Surface Antigen Diagnostic Performance in Chronic Hepatitis B Virus-Infected Patients

Source : https://www.cureus.com/articles/162477-evaluation-and-determination-of-quantitative-hepatitis-b-surface-antigen-diagnostic-performance-in-chronic-hepatitis-b-virus-infected-patients

Background Hepatitis B virus DNA (HBV-DNA) assessment is recommended for diagnosing and monitoring chronic hepatitis B (CHB) patients. Quantitative hepatitis B surface antigen (qHBsAg) estimation adjunct to HBV-DNA is vital...

Conclusions: Our results indicated that qHBsAg might be a useful marker for monitoring HBV-DNA in CHB patients throughout treatment and follow-up.

  • Saved
Comprehensive analysis of the microbiome and metabolome in pus from pyogenic liver abscess patients with and without diabetes mellitus

Comprehensive analysis of the microbiome and metabolome in pus from pyogenic liver abscess patients with and without diabetes mellitus

Source : https://doi.org/10.3389/fmicb.2023.1211835

IntroductionPyogenic liver abscess (PLA) patients combined with diabetes mellitus (DM) tend to have more severe clinical manifestations than without DM. The mechanism responsible for this phenomenon is not entirely clear....

Discussion: The results showed that the relative abundance of Klebsiella in the pus cavity of PLA patients with DM was higher than those without DM, accompanied by changes of various metabolites and metabolic pathways, which may be associated with more severe clinical manifestations.