Evolocumab on top of empagliflozin improves endothelial function of individuals with diabetes: randomized active-controlled trial - Cardiovascular Diabetology
Source : https://cardiab.biomedcentral.com/articles/10.1186/s12933-022-01584-8
Background Sodium-glucose cotransporter 2 inhibitors (SGLT2i) improve endothelial dysfunction and reduce cardiovascular events in individuals with type 2 diabetes (T2D). Proprotein convertase subtilisin/kexin 9 (PCSK9i) inhibitors reduce cardiovascular events in...
Conclusions: In individuals with T2D, the addition of evolocumab on top of empagliflozin improves endothelial function.
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New Therapeutic Approaches in Treatment of Dyslipidaemia-A Narrative Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35890138/
Dyslipidaemia is a well-known risk factor for the development of cardiovascular disease, a leading cause of morbidity and mortality in developed countries. As a consequence, the medical community has been...
Conclusion: This article provides a short summary of new agents currently used or being developed for lipid lowering treatment.
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Clinical Aspects of Genetic and Non-Genetic Cardiovascular Risk Factors in Familial Hypercholesterolemia - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35885941/
1 Division of Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary. 2 Division of Endocrinology, Department of Internal Medicine, Faculty of Medicine, University of...
Conclusion: In this review, we summarize the most important genetic and non-genetic factors that might affect the risk prediction and therapeutic strategy in FH through the eyes of clinicians focusing on disorders that might not be in the center of FH research. The review highlights the complexity of FH care and the need of an...
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Cardiac rehabilitation performance predicts 1-year major adverse cardiovascular events - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35904222/
doi: 10.1002/clc.23890. Online ahead of print. 1 Internal Medicine, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA. 2 School of Medicine, University of...
Conclusion: Our proposed CR-score accurately identifies patients at high risk for 1-year MACE following the rehabilitation program. Multicenter validation is required.
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Conclusions: SVI varies across the US states and is associated with prevalent cardiovascular comorbidities and ASCVD, independent of age, race and ethnicity, sex, employment, income, and health care coverage. SVI may be a useful assessment tool for health policy makers and health systems researchers examining multilevel influences on...
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