Lipid Management Connect
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Four-year HbA1c and LDL-cholesterol trajectories among individuals with mental disorders and newly developed type 2 diabetes - PubMed

Four-year HbA1c and LDL-cholesterol trajectories among individuals with mental disorders and newly developed type 2 diabetes - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34543525/

The impact of different types of mental disorders on long-term glycemic and lipid trajectories following newly diagnosed type 2 diabetes (T2D) remains unknown. We used real-world clinical data in a...

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Conclusions and Relevance This cohort study showed that cumulative LDL-C and TWA LDL-C during young adulthood and middle age were associated with the risk of incident CHD, independent of midlife LDL-C level. These findings suggest that past levels of LDL-C may inform strategies for primary prevention of CHD and that maintaining optimal LDL-C...

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LDL-cholesterol drives reversible myelomonocytic skewing in human bone marrow - PubMed

LDL-cholesterol drives reversible myelomonocytic skewing in human bone marrow - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34508568/

doi: 10.1093/eurheartj/ehab630. Online ahead of print. 1 Institut National de la Santé et de la Recherche Médicale (INSERM) U1065, Université Côte d'Azur, Centre Méditerranéen de Médecine Moléculaire (C3M), Atip-Avenir, Fédération...

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Perspectives on Identifying and Treating Familial Hypercholesterolemia in Childhood - PubMed

Perspectives on Identifying and Treating Familial Hypercholesterolemia in Childhood - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34491300/

doi: 10.1093/clinchem/hvab157. Online ahead of print. 1 Department of Cardiology, Boston Children's Hospital, Boston, MA. 2 Dept. of Pediatrics, Harvard Medical School, Boston, MA USA. 3 Richard A. and Susan...

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Effects of different doses of atorvastatin on blood lipid level and endothelial function in patients with hypertension and carotid plaque | Chinese Journal of Primary Medicine and Pharmacy;(12): 563-567, 2021. | WPRIM

Source : https://pesquisa.bvsalud.org/portal/resource/pt/wpr-883783

To compare the effects of different doses of atorvastatin on blood lipid and endothelial function in patients with hypertension and carotid plaque. Ninety-two patients with hypertension and carotid plaque who...

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    Key Points • Conclusion/Relevance: “People with a small asymptomatic AAA are at high risk of MVE [major vascular events] and PVE [peripheral vascular events]. This study provides evidence of the possible benefits Show More
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Efficacy of intensive lipid-lowering therapy with statins stratified by blood pressure levels in patients with type 2 diabetes mellitus and retinopathy: Insight from the EMPATHY study - Hypertension Research

Efficacy of intensive lipid-lowering therapy with statins stratified by blood pressure levels in patients with type 2 diabetes mellitus and retinopathy: Insight from the EMPATHY study - Hypertension Research

Source : https://www.nature.com/articles/s41440-021-00734-x

Intensive lipid-lowering therapy is recommended in individuals exhibiting type 2 diabetes mellitus (T2DM) with microvascular complications (as high-risk patients), even without known cardiovascular disease (CVD). However, evidence is insufficient to...

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Relationship between serum lipid levels and ischemic stroke in patients with atrial fibrillation: a nested case-control study based on the China Atrial Fibrillation Registry - BMC Cardiovascular Disorders

Relationship between serum lipid levels and ischemic stroke in patients with atrial fibrillation: a nested case-control study based on the China Atrial Fibrillation Registry - BMC Cardiovascular Disorders

Source : https://link.springer.com/article/10.1186/s12872-021-02237-6

Background Atrial fibrillation (AF) is an important risk factor for acute ischemic stroke. Methods A nested case-control study was conducted among patients diagnosed with AF, whose information was acquired from...

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Use of statin for the primary prevention of cardiovascular outcomes in elderly patients: A propensity-matched cohort study - PubMed

Use of statin for the primary prevention of cardiovascular outcomes in elderly patients: A propensity-matched cohort study - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34126505/

doi: 10.1016/j.atherosclerosis.2021.05.022. 1 Division of Endocrinology and Metabolism, Department of Internal Medicine, Inha University College of Medicine, Incheon, South Korea. 2 Department of Biostatistics, Korea University College of Medicine, Seoul,...

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    In participants with type 2 diabetes, statin treatment was associated with a reduction in ischemic stroke !
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Study Suggests 'Remnant Cholesterol' As Stand-alone Risk for Heart Attack and Stroke

Study Suggests 'Remnant Cholesterol' As Stand-alone Risk for Heart Attack and Stroke

Source : https://www.hopkinsmedicine.org/news/newsroom/news-releases/study-suggests-remnant-cholesterol-as-stand-alone-risk-for-heart-attack-and-stroke

Remnant cholesterol represents the amount of cholesterol in remnant lipoproteins, a form of very low-density lipoproteins (VLDL) from which sugary fatty acids - called triglycerides - have been removed. Along...

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    One-third of all deaths in this country are attributed to heart disease, stroke and other cardiovascular disease
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[Acupuncture intervention induced improvement of oxidative stress by regulating PKCβ/P66shc signaling in obese diabetic rats].

Source : https://europepmc.org/article/med/34472748

Objective To observe the effect of electroacupuncture (EA) at "Zusanli"(ST36)-"Sanyinjiao"(SP6) on glucose and lipid metabolism and insulin resistance (IR) in obese diabetic rats, so as to explore its mechanism underlying...

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    Key Points • Conclusion/Relevance: “The incidence of occurrence of dyslipidemia is very high in type 2 diabetic patients. Hyperlipidemia is a common complication of diabetes mellitus, provoking them to develop atherosclerosis and Show More
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Metabolic Changes in SARS-CoV-2 Infection: Clinical Data and Molecular Hypothesis to Explain Alterations of Lipid Profile and Thyroid Function Observed in COVID-19 Patients

Metabolic Changes in SARS-CoV-2 Infection: Clinical Data and Molecular Hypothesis to Explain Alterations of Lipid Profile and Thyroid Function Observed in COVID-19 Patients

Source : https://www.mdpi.com/2075-1729/11/8/860

It seems that during SARS-CoV-2 infection, total cholesterol, LDL-C, and HDL-C values decrease and lipids could play a fundamental role in viral replication. Moreover, it has been shown that SARS-CoV-2...

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Male-specific Association between Iron and Lipid Metabolism Changes and Erythroferrone after Hepatitis C Virus Eradication - PubMed

Male-specific Association between Iron and Lipid Metabolism Changes and Erythroferrone after Hepatitis C Virus Eradication - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34433710/

Objective Hepatitis C virus (HCV) eradication is associated with decreased serum ferritin and increased serum low-density lipoprotein-cholesterol (LDL-C) levels, although the mechanisms underlying these changes remain unclear. This study aimed...

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Lycopene Reduces Cholesterol Absorption and Prevents Atherosclerosis in ApoE-/- Mice by Downregulating HNF-1α and NPC1L1 Expression

Lycopene Reduces Cholesterol Absorption and Prevents Atherosclerosis in ApoE-/- Mice by Downregulating HNF-1α and NPC1L1 Expression

Source : https://pubs.acs.org/doi/abs/10.1021/acs.jafc.1c03160

Our previous study showed that lycopene reduced the absorption of cholesterol in Caco-2 cells through inhibiting Niemann-Pick C1-Like 1 (NPC1L1) expression. Herein, we aimed to explore whether lycopene supplementation can...

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Early postpartum abnormal glucose metabolism subtype differs according to mid-trimester lipid profile in women with gestational diabetes mellitus - Lipids in Health and Disease

Early postpartum abnormal glucose metabolism subtype differs according to mid-trimester lipid profile in women with gestational diabetes mellitus - Lipids in Health and Disease

Source : https://lipidworld.biomedcentral.com/articles/10.1186/s12944-021-01519-4

Background It is unknown whether early postpartum abnormal glucose metabolism (AGM) in women with previous gestational diabetes mellitus (GDM) is related to their mid-trimester lipid profile. The aim of this...

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