Four-year HbA1c and LDL-cholesterol trajectories among individuals with mental disorders and newly developed type 2 diabetes - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34543525/
The impact of different types of mental disorders on long-term glycemic and lipid trajectories following newly diagnosed type 2 diabetes (T2D) remains unknown. We used real-world clinical data in a...
Conclusions and Relevance This cohort study showed that cumulative LDL-C and TWA LDL-C during young adulthood and middle age were associated with the risk of incident CHD, independent of midlife LDL-C level. These findings suggest that past levels of LDL-C may inform strategies for primary prevention of CHD and that maintaining optimal LDL-C...
LDL-cholesterol drives reversible myelomonocytic skewing in human bone marrow - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34508568/
doi: 10.1093/eurheartj/ehab630. Online ahead of print. 1 Institut National de la Santé et de la Recherche Médicale (INSERM) U1065, Université Côte d'Azur, Centre Méditerranéen de Médecine Moléculaire (C3M), Atip-Avenir, Fédération...
Perspectives on Identifying and Treating Familial Hypercholesterolemia in Childhood - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34491300/
doi: 10.1093/clinchem/hvab157. Online ahead of print. 1 Department of Cardiology, Boston Children's Hospital, Boston, MA. 2 Dept. of Pediatrics, Harvard Medical School, Boston, MA USA. 3 Richard A. and Susan...
Nutrient Patterns are Associated with Discordant Apolipoprotein B and Low-Density Lipoproteins: A Population-Based Analysis | British Journal of Nutrition | Cambridge Core
HTML view is not available for this content. However, as you have access to this content, a full PDF is available via the 'Save PDF' action button. Individuals with discordantly...
Effects of different doses of atorvastatin on blood lipid level and endothelial function in patients with hypertension and carotid plaque | Chinese Journal of Primary Medicine and Pharmacy;(12): 563-567, 2021. | WPRIM
Source : https://pesquisa.bvsalud.org/portal/resource/pt/wpr-883783
To compare the effects of different doses of atorvastatin on blood lipid and endothelial function in patients with hypertension and carotid plaque. Ninety-two patients with hypertension and carotid plaque who...
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Lipid Management Connect5yrKey Points • Conclusion/Relevance: “People with a small asymptomatic AAA are at high risk of MVE [major vascular events] and PVE [peripheral vascular events]. This study provides evidence of the possible benefits Show More
Efficacy of intensive lipid-lowering therapy with statins stratified by blood pressure levels in patients with type 2 diabetes mellitus and retinopathy: Insight from the EMPATHY study - Hypertension Research
Source : https://www.nature.com/articles/s41440-021-00734-x
Intensive lipid-lowering therapy is recommended in individuals exhibiting type 2 diabetes mellitus (T2DM) with microvascular complications (as high-risk patients), even without known cardiovascular disease (CVD). However, evidence is insufficient to...
Relationship between serum lipid levels and ischemic stroke in patients with atrial fibrillation: a nested case-control study based on the China Atrial Fibrillation Registry - BMC Cardiovascular Disorders
Source : https://link.springer.com/article/10.1186/s12872-021-02237-6
Background Atrial fibrillation (AF) is an important risk factor for acute ischemic stroke. Methods A nested case-control study was conducted among patients diagnosed with AF, whose information was acquired from...
Use of statin for the primary prevention of cardiovascular outcomes in elderly patients: A propensity-matched cohort study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34126505/
doi: 10.1016/j.atherosclerosis.2021.05.022. 1 Division of Endocrinology and Metabolism, Department of Internal Medicine, Inha University College of Medicine, Incheon, South Korea. 2 Department of Biostatistics, Korea University College of Medicine, Seoul,...
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Dr Hamid5yrIn participants with type 2 diabetes, statin treatment was associated with a reduction in ischemic stroke !
Study Suggests 'Remnant Cholesterol' As Stand-alone Risk for Heart Attack and Stroke
Remnant cholesterol represents the amount of cholesterol in remnant lipoproteins, a form of very low-density lipoproteins (VLDL) from which sugary fatty acids - called triglycerides - have been removed. Along...
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Dr Hamid5yrOne-third of all deaths in this country are attributed to heart disease, stroke and other cardiovascular disease
[Acupuncture intervention induced improvement of oxidative stress by regulating PKCβ/P66shc signaling in obese diabetic rats].
Source : https://europepmc.org/article/med/34472748
Objective To observe the effect of electroacupuncture (EA) at "Zusanli"(ST36)-"Sanyinjiao"(SP6) on glucose and lipid metabolism and insulin resistance (IR) in obese diabetic rats, so as to explore its mechanism underlying...
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Lipid Management Connect5yrKey Points • Conclusion/Relevance: “The incidence of occurrence of dyslipidemia is very high in type 2 diabetic patients. Hyperlipidemia is a common complication of diabetes mellitus, provoking them to develop atherosclerosis and Show More
Metabolic Changes in SARS-CoV-2 Infection: Clinical Data and Molecular Hypothesis to Explain Alterations of Lipid Profile and Thyroid Function Observed in COVID-19 Patients
Source : https://www.mdpi.com/2075-1729/11/8/860
It seems that during SARS-CoV-2 infection, total cholesterol, LDL-C, and HDL-C values decrease and lipids could play a fundamental role in viral replication. Moreover, it has been shown that SARS-CoV-2...
Male-specific Association between Iron and Lipid Metabolism Changes and Erythroferrone after Hepatitis C Virus Eradication - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34433710/
Objective Hepatitis C virus (HCV) eradication is associated with decreased serum ferritin and increased serum low-density lipoprotein-cholesterol (LDL-C) levels, although the mechanisms underlying these changes remain unclear. This study aimed...
Lycopene Reduces Cholesterol Absorption and Prevents Atherosclerosis in ApoE-/- Mice by Downregulating HNF-1α and NPC1L1 Expression
Source : https://pubs.acs.org/doi/abs/10.1021/acs.jafc.1c03160
Our previous study showed that lycopene reduced the absorption of cholesterol in Caco-2 cells through inhibiting Niemann-Pick C1-Like 1 (NPC1L1) expression. Herein, we aimed to explore whether lycopene supplementation can...
Early postpartum abnormal glucose metabolism subtype differs according to mid-trimester lipid profile in women with gestational diabetes mellitus - Lipids in Health and Disease
Source : https://lipidworld.biomedcentral.com/articles/10.1186/s12944-021-01519-4
Background It is unknown whether early postpartum abnormal glucose metabolism (AGM) in women with previous gestational diabetes mellitus (GDM) is related to their mid-trimester lipid profile. The aim of this...