Molecular genetics for familial hypercholesterolemia
Source : https://imrpress.com/journal/RCM/23/1/10.31083/j.rcm2301004
IMR Press is a leading publisher of open access peer-reviewed biomedical and life sciences journals. We aim to facilitate the dissemination of high-quality research in the area of biomedical science....
Conclusion/Relevance: "These results permit the following conclusions: (a) when participants were solely ascertained for abnormal LDL cholesterol level (>190 mg/dL), we identified an FH mutation in 25.05% of hypercholesterolemic patients. These sequencing yelds are partially overlapping with other previous screening studies [7, 8]; (b) CAD...
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Laparoscopic diagnosis of idiopathic left ovarian vein thrombosis in a 27-year-old woman - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35096407/
Idiopathic left ovarian vein thrombosis was diagnosed in a 27-year-old woman at the time of a diagnostic laparoscopy performed because of a suspected ovarian torsion. The diagnosis was confirmed by...
Relevance: During follow-up it became clear that the patient was already diagnosed with familial hypercholesterolemia before the occurrence of the ovarian vein thrombosis. It remains unclear if familial hypercholesterolemia played a role in the occurrence of ovarian vein thrombosis in our patient.
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THE EFFECT OF EVOLOCUMAB ALONE AND IN COMBINATION WITH ATORVASTATIN ON LIPID PROFILE - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35058387/
Conclusions: Preproteins convert as esubtilisin/kexin type 9 inhibitor regulates the serum levels of lipid and cholesterol by lowering LDL-C, and the results also indicate that combination of evolocumab and atorvastatin...
Conclusion: Preproteins convert as esubtilisin/kexin type 9 inhibitor regulates the serum levels of lipid and cholesterol by lowering LDL-C, and the results also indicate that combination of evolocumab and atorvastatin are more potent in lowering the lipid profile and then reduce progression of atherosclerosis than evolocumab alone in rabbits...
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Daily intake of up to two eggs for 11 weeks does not affect the cholesterol balance of Chinese young adults
Source : https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.2734
Dexin Zhang , Deyuan Li , Fang Yang , Corresponding Author Fang Yang School of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, China Correspondence Deyuan Li, Functional Food Research,...
These results demonstrate that intake of up to two eggs a day had little effect on biomarkers of CVDs in young, healthy Chinese college students and provided useful evidence for the dietary guidelines regarding egg consumption.
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The Impact of the COVID-19 Outbreak on Patients’ Adherence to PCSK9 Inhibitors Therapy
Source : https://www.mdpi.com/2077-0383/11/3/475/htm
PCSK9 inhibitors (PCSK9i) are monoclonal antibodies that have been shown to be effective in reducing both LDL cholesterol (LDL-C) values and major cardiovascular events in patients at high cardiovascular risk....
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Dr Hamid4yrFacilitating patients’ access to PCSK9i and enhancing telemedicine seem to be effective strategies to ensure the continuity of care and appropriate management of these patients.